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This section includes InterviewSolutions, each offering curated multiple-choice questions to sharpen your knowledge and support exam preparation. Choose a topic below to get started.
| 251. |
A lipid bilayer is permeable to (A) Urea (B) Fructose (C) Glucose (D) Potassium |
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Answer» A lipid bilayer is permeable to Urea. |
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| 252. |
Which of the following enzyme is responsible for making a DNA copy from RNA?(a) Reverse transcriptase(b) DNA polymerase(c) RNA polI(d) RNA polII |
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Answer» The correct choice is (a) Reverse transcriptase Best explanation: Reverse transcriptase generates complementary DNA from RNA template. |
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| 253. |
Which of the following is true about tm?(a) It can be termed as renaturation temperature(b) The higher the content of G ≡ C base pairs, the higher the tm(c) The higher the content of A = T base pairs, the higher the tm(d) The higher the content of G ≡ C base pairs, the lower the tm |
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Answer» Right choice is (b) The higher the content of G ≡ C base pairs, the higher the tm The best I can explain: Tm is the melting temperature or denaturation temperature. |
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| 254. |
What happens in hypochromicity?(a) When DNA is in bound form, there is decrease in absorption of UV light(b) When DNA is in bound form, there is increase in absorption of UV light(c) When DNA is in unbound form, it is more stable(d) When DNA is in unbound form, there is decrease in absorption of UV light |
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Answer» The correct option is (a) When DNA is in bound form, there is decrease in absorption of UV light The best explanation: It describes the decrease in absorbance of UV light in a double stranded DNA. |
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| 255. |
Which of the following is a sphingophospholipid?(a) Lecithin(b) Sphingomyelin(c) Plasmolegen(d) Cardiolipin |
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Answer» Correct option is (b) Sphingomyelin For explanation: Lecithin, plasmolegen and cardiolipin are glycerophospholipids. |
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| 256. |
What happens in hyperchromicity?(a) When DNA is in bound form, there is decrease in absorption of UV light(b) When DNA is in bound form, there is increase in absorption of UV light(c) When DNA is in unbound form, it is more stable(d) When DNA is in unbound form, there is increase in absorption of UV light |
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Answer» Correct answer is (d) When DNA is in unbound form, there is increase in absorption of UV light Explanation: It describes the increase in absorption of UV light in a single stranded DNA. |
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| 257. |
The sugar molecule in a nucleotide is ____________(a) Pentose(b) Hexose(c) Tetrose(d) Triose |
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Answer» Right choice is (a) Pentose Easy explanation: Ribose or deoxyribose is a 5 carbon sugar. |
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| 258. |
Which of the following statements is true?(a) Sugar component of a nucleotide is ribose(b) Sugar component of a nucleotide is deoxyribose(c) The bases in nucleotides are attached to a pentose sugar moiety by a glycosidic linkage(d) The sugar molecule of the nucleotide is in L-configuration |
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Answer» Right option is (c) The bases in nucleotides are attached to a pentose sugar moiety by a glycosidic linkage For explanation: Sugar component of a nucleotide may be ribose or deoxyribose. |
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| 259. |
What is the composition of nucleotide?(a) a sugar + a phosphate(b) a base + a sugar(c) a base + a phosphate(d) a base + a sugar + phosphate |
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Answer» Correct answer is (d) a base + a sugar + phosphate Best explanation: A nucleotide is composed of a base, a sugar and a phosphate. |
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| 260. |
The allosteric inhibitor of an enzyme ___________(a) Causes the enzyme to work faster(b) Binds to the active site(c) Participates in feedback regulation(d) Denatures the enzyme |
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Answer» The correct answer is (c) Participates in feedback regulation Best explanation: In feedback regulation, enzyme is not directly inhibited by the end product instead its synthesis is inhibited by interfering with the gene of that enzyme. |
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| 261. |
Which of the following blood group individuals have N-acetylgalactosamine sugar attachment?(a) A(b) B(c) AB(d) O |
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Answer» Right choice is (a) A Explanation: A blood group of individuals have N-acetylgalactosamine sugar attachment. |
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| 262. |
The red precipitate formed when glucose is heated with “Benedict’s reagent” is ___________(a) Cupric hydroxide(b) Cuprous hydroxide(c) Cupric oxide(d) Cuprous oxide |
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Answer» Correct option is (d) Cuprous oxide To explain: When reducing sugars are heated in the presence of an alkali and reduce the Cupric compounds present in the Benedict’s reagent to cuprous compounds which get precipitated as insoluble red Cu2O. |
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| 263. |
Which of the following blood group individuals have galactose?(a) A(b) B(c) AB(d) O |
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Answer» Right option is (b) B Explanation: B blood group individuals have galactose. |
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| 264. |
Which of the following are not the components of RNA?(a) Thymine(b) Adenine(c) Guanine(d) Cytosine |
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Answer» Right answer is (a) Thymine The best I can explain: Thymine is present in DNA but not in RNA. |
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| 265. |
DNA denaturation is measured by absorbance at ___________(a) 220nm(b) 230nm(c) 250nm(d) 260nm |
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Answer» Correct answer is (d) 260nm The best I can explain: At 260nm absorbance, DNA denaturation is measured. |
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| 266. |
Which of the following can be termed as a restriction modification system?(a) Restriction endonuclease + methylase(b) DNA ligase + methylase(c) Restriction endonuclease + acetylase(d) DNA ligase + acetylase |
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Answer» Right option is (a) Restriction endonuclease + methylase To elaborate: (Restriction endonuclease + methylase) is termed as a restriction modification system. |
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| 267. |
Which of the following enzyme is used in PCR?(a) Taq DNA polymerase(b) HRP(c) EcoRI(d) EcoRII |
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Answer» The correct answer is (a) Taq DNA polymerase To explain: HRP is an enzyme used in ELISA. EcorI and EcorII are the restriction enzymes. So only a DNA polymerase is responsible for producing multiple copies of DNA sequence. |
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| 268. |
Which of the following is false about denaturation?(a) Disruption of hydrogen bonds(b) Disruption of phosphodiester linkage(c) Loss of helical structure of DNA(d) It is resulted as a result of change in pH or increase in temperature |
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Answer» Correct option is (b) Disruption of phosphodiester linkage To explain: Phosphodiester linkages are not broken by denaturation. |
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| 269. |
In mammalian cells rRNA is produced mainly in the (A) Endoplasmic reticulum (B) Ribosome (C) Nucleolus (D) Nucleus |
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Answer» In mammalian cells rRNA is produced mainly in the Nucleolus. |
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| 270. |
Mature erythrocytes do not contain (A) Glycolytic enzymes(B) HMP shunt enzymes (C) Pyridine nucleotide(D) ATP |
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Answer» (C) Pyridine nucleotide |
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| 271. |
Enzymes catalyzing electron transport are present mainly in the (A) Ribosomes (B) Endoplasmic reticulum (C) Lysosomes (D) Inner mitochondrial membrane |
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Answer» (D) Inner mitochondrial membrane |
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| 272. |
At pH 7.4, the ratio of bicarbonate : dissolved CO2 is (A) 1 : 1 (B) 10 : 1 (C) 20 : 1 (D) 40 : 1 |
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Answer» At pH 7.4, the ratio of bicarbonate : dissolved CO2 is 20 : 1. |
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| 273. |
Edema can occur when |
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Answer» Edema can occurs when tiny blood vessels in your body (capillaries) leak fluid. The fluid builds up in surrounding tissues, leading to swelling. |
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| 274. |
In which of the following means of transport a cell expels large molecules out of it?(a) Phagocytosis(b) Exocytosis(c) Endocytosis(d) Diffusion |
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Answer» Right choice is (b) Exocytosis Easiest explanation: In exocytosis, a cell expels large molecules out of it. |
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| 275. |
Which out of the following is not mediated transport?(a) Facilitated diffusion(b) Primary active transport(c) Secondary active transport(d) Simple diffusion |
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Answer» Correct option is (d) Simple diffusion For explanation I would say: Simple diffusion is not mediated transport. |
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| 276. |
Which of the following mixture in aqueous solution of equimolar concentration acts as a buffer solution?(a) HNO3 + NaOH(b) H2 SO4 + KOH(c) NH4 OH(excess) + HCl(d) CH3 COOH + NaOH(excess) |
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Answer» The correct answer is (c) NH4 OH(excess) + HCl The explanation is: NH4 OH(excess) + HCl → NH4 Cl + H2O So the mixture contains NH4 OH + NH4 Cl. |
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| 277. |
Important finding of secondary dehydration is(A) Intracellular oedema(B) Cellular dehydration(C) Thirst(D) Muscle cramps |
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Answer» Important finding of secondary dehydration is intracellular oedema. |
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| 278. |
Which can act as buffer?(a) NH4 Cl + HCl(b) CH3 COOH + H2 CO3(c) 40ml of 0.1M NaCN + 20ml of 0.1M HCN(d) NaCl + NaOH |
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Answer» Right answer is (c) 40ml of 0.1M NaCN + 20ml of 0.1M HCN Easy explanation: It is a mixture of weak acid and its salt with strong base. |
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| 279. |
Which technique is preferred in the separation of fatty acyl methyl esters from a mixture?(a) Gas-liquid chromatography(b) Absorption chromatography(c) TLC(d) Centrifugation |
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Answer» The correct option is (a) Gas-liquid chromatography Explanation: Gas liquid chromatography or HPLC is preferred in the separation of fatty acyl methyl esters from a mixture. |
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| 280. |
Which of the following hormone is responsible for the activation of phospholipase C?(a) Serotonin(b) Cortisol(c) Vasopressin(d) Adrenaline |
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Answer» Correct option is (c) Vasopressin Explanation: Vasopressin, when it binds to the plasma membrane receptors on the epithelial cells of the renal collecting duct, a specific phospholipase C is activated. |
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| 281. |
Which of the following is a 39-residue hormone of the anterior pituitary gland?(a) Corticotropin(b) Glucagon(c) Insulin(d) Bradykinin |
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Answer» The correct option is (a) Corticotropin To elaborate: Corticotropin is a 39-residue hormone of the anterior pituitary gland that stimulates the adrenal cortex. |
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| 282. |
Which of the following enzyme is required for end to end joining of DNA?(a) DNA ligase(b) Restriction endonuclease(c) RNA polymerase(d) DNA polymerase |
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Answer» The correct option is (a) DNA ligase The best explanation: DNA ligase ligates both blunt and sticky ends of DNA. |
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| 283. |
Unfolding of a protein can be termed as _________(a) Renaturation(b) Denaturation(c) Oxidation(d) Reduction |
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Answer» Correct option is (b) Denaturation The explanation is: The proteins lose their quaternary, tertiary, secondary structure and return to its native state by denaturation process. |
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| 284. |
Which of the following is not the function of helper T cells is ____________(a) Produce soluble signaling proteins called cytokines, which include the interleukins(b) They help activate cytotoxic T cells to kill infected target cells(c) They help activate B cells to secrete antibodies and macrophages to destroy ingested microbes(d) They recognize and bind extracellular ligands |
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Answer» Right choice is (d) They recognize and bind extracellular ligands Easy explanation: The function of TH cells is to interact with macrophages and secrete cytokines that stimulate TC, TH and B cells to proliferate. |
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| 285. |
In the binding of oxygen to myoglobin, the relationship between the concentration of oxygen and the fraction of binding sites occupied can best be described as ___________(a) Hyperbolic(b) Linear with a negative slope(c) Linear with a positive slope(d) Parabolic |
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Answer» Right choice is (a) Hyperbolic To explain I would say: The equation θ=(pO2)/(pO2 +P50) is of the form y = x/(x+z) which describes hyperbola. |
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| 286. |
Myoglobin is particularly abundant in ________(a) Nerves(b) Muscles(c) Blood cells(d) Skin |
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Answer» Correct choice is (b) Muscles The explanation is: As a transport protein, it facilitates O2 diffusion in muscle. |
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| 287. |
His^93 is also called ________(a) His F8(b) His F7(c) His F6(d) His F5 |
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Answer» The correct answer is (a) His F8 The best explanation: His^93, the 93^rd amino acid residue from the amino-terminal end of the myoglobin polypeptide sequence is also called His F8, the 8th residue in α helix F. |
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| 288. |
The most abundant immunoglobulin is ____________(a) IgA(b) IgE(c) IgG(d) IgM |
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Answer» Correct option is (c) IgG Explanation: IgG is the most abundant antibody found in all body fluids. |
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| 289. |
If pH of solution of NaOH is 12.0 the pH of H2 SO4 solution of same molarity will be?(a) 2.0(b) 12.0(c) 1.7(d) 10.0387 |
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Answer» Right answer is (c) 1.7 The best I can explain: pH = 12 then pOH = 2 [OH^–] = 10^-2 Molarity of NaOH = 10^-2 For H2 SO4, molarity = 10^-2 [H^+] = 2 × 10^-2 pH = 2 – log2 = 1.7. |
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| 290. |
Movement of phospholipids from side to side is called ____________(a) Facilitated diffusion(b) Lateral diffusion(c) Transverse diffusion(d) Simple diffusion |
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Answer» Right choice is (b) Lateral diffusion Easy explanation: In lateral diffusion, movement of phospholipids from side to side. |
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| 291. |
Short DNA sequence having single occurrence in genome is ____________(a) Expressed sequence tag(b) Sequence tagged site(c) Contig(d) YAC |
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Answer» Right choice is (b) Sequence tagged site Explanation: Expressed sequence tag is a short sub-sequence of a cDNA sequence. Cotig is a set of overlapping DNA segments that together represent a consensus region of DNA. YAC is a linear DNA molecule. |
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| 292. |
During DNA profiling, DNA nucleotides hybridized with the probe can be detected through ____________(a) Electrophoresis(b) Polymerase chain reaction(c) Autoradiography(d) Hybridoma |
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Answer» Correct option is (c) Autoradiography To elaborate: Autoradiography is a detection method in hybridization. |
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| 293. |
Which of the following phospholipids is a component of inner mitochondrial membrane?(a) Plasmologen(b) Cephalin(c) Lecithin(d) Cardiolipin |
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Answer» Right answer is (d) Cardiolipin The best explanation: Cardiolipin is an essential component of inner mitochondrial membrane. |
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| 294. |
D-galactos and D-glucose are. |
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Answer» The sugars glucose and galactose are epimers. In glucose, the -OH group on the first carbon is in the axial position, the direction opposite the -OH group on carbon C-4. In galactose, the -OH group is oriented in the same direction, the equatorial position. |
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| 295. |
One joule is the energy required to (A) Raise the temperature of 1 gm of water by 1°C (B) Raise the temperature of 1 kg of water by 1°C (C) Move a mass of 1 gm by 1 cm distance by a force of 1 Newton (D) Move a mass of 1 kg by 1 m distance by a force of 1 Newton |
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Answer» One joule is the energy required to raise the temperature of 1 gm of water by 1°C. Calorie (cal) is the energy needed to increase 1 gram of water by 1°C at a pressure of 1 atmosphere. 1 cal = 4.184 J. So 1J = 0.24 cal. |
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| 296. |
Which of the following is an imino acid?(a) Alanine(b) Glycine(c) Proline(d) Serine |
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Answer» The correct option is (c) Proline Easiest explanation: Proline is secondary amino acid also called as an imino acid as it contains –C = NH – OH group. |
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| 297. |
Which of the following is true about Michaelis-Menten kinetics?(a) Km, the Michaelis constant, is defined as that concentration of substrate at which enzyme is working at maximum velocity(b) It describes single substrate enzymes(c) Km, the Michaelis constant is defined as the dissociation constant of the enzyme-substrate complex(d) It assumes covalent binding occurs between enzyme and substrate |
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Answer» The correct answer is (b) It describes single substrate enzymes To explain: Km is defined as the concentration of substrate at which enzyme is working at half of maximum velocity. It is also a measure of the affinity that the enzyme has for its substrate. Michaelis-Menten kinetics assumes non-covalent binding between enzyme and substrate. |
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| 298. |
Which of the following is an example of reversible inhibitor?(a) DIPF(b) Penicillin(c) Iodoacetamide(d) Protease inhibitors |
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Answer» Right answer is (d) Protease inhibitors To explain: DIPF, Penicillin and Iodoacetamide are irreversible inhibitors. |
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| 299. |
Which of the following is an example for irreversible inhibitor?(a) Disulfiram(b) Oseltamivir(c) Protease inhibitors(d) DIPF |
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Answer» The correct choice is (d) DIPF To explain: Disulfiram, Oseltamivir and protease inhibitors are reversible inhibitors. |
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| 300. |
How many steps are catalyzed by the same enzymes in both glycolysis and gluconeogenesis?(a) 6(b) 7(c) 8(d) 9 |
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Answer» Right choice is (b) 7 Easiest explanation: Phosphohexose isomerase, aldolase, triose phosphate isomerase, glyceraldehyde phosphate dehydrogenase, phosphoglycerate kinase, phosphoglycerate mutase and enolase are the enzymes which catalyze the reactions in both glycolysis and gluconeogenesis. |
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