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This section includes InterviewSolutions, each offering curated multiple-choice questions to sharpen your knowledge and support exam preparation. Choose a topic below to get started.
| 351. |
Which of the following is true with respect of AUGA. it codes for methionine onlyB. It is an initiation codonC. It codes for methionine in both prokaryotes and eukaryotesD. All of the above |
| Answer» Correct Answer - d | |
| 352. |
Nobel Prize for one gene one enzyme hypothesis was given toA. Watson and CrickB. Sutton and BoveriC. Avery etalD. Beadle and Tatum |
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Answer» Correct Answer - D Noble Prize (1958) for one gene one enzyme hypothesis was given to Beadle and Tatum. |
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| 353. |
The polymerase chain reaction is a technique thatA. Is used for in vivo replication of DNAB. `Is used for in vivo synthesis of m RNA`C. `Is used for in vitro synthesis of mRNA`D. `Used for in virto replication of specific DNA sequence using thermostable DNA polymerase` |
| Answer» Correct Answer - d | |
| 354. |
Polymerase chain reaction is most useful inA. DNA synthesisB. DNA amplificationC. Protein synthesisD. Amino acid synthesis |
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Answer» Correct Answer - b b) PCR is a method for amplyfying a specific piece of DNA molecule without the requirements for time-consuming cloning procedures. |
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| 355. |
VNTR is used in :A. Protoplast cultureB. DNA finger printingC. regulation of hormonesD. enhancing photosynthetic genes |
| Answer» Correct Answer - B | |
| 356. |
Lac operon concept was proposed byA. Jacob and Monod in 1961B. Jacob and Monod in 1969C. Watson and Crick in 1953D. Watson ad Crick in 1963 |
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Answer» Correct Answer - A Lac operon concept was proposed by Jacob and Monod in 1961. |
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| 357. |
Write the names of various nitrogenous bases found in RNA. |
| Answer» Adenine, uracil, guanine, cytosine. | |
| 358. |
What do you understand by genome. |
| Answer» A complete set of genes contained in the haploid dose of chromosomes and inherited as a unit from one parent is called genome. | |
| 359. |
Explain the role of enzymes nucleases and ligases. |
| Answer» Nucleases remove unwanted nucleotides while ligases rejoin useful regions of nucleic acid (RNA). | |
| 360. |
Biochemical natural of genetic material was not defined fromA. Transforming principleB. Hershey and Chase experimentC. Avery, Machleod and McCartyD. None of the above |
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Answer» Correct Answer - A Biochemical nature of gentic material was not defined from transforming principle. |
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| 361. |
Which out of the following statement is incorrect ?A. Genetic code is ambiguousB. Genetic code is degenerateC. Genetic code is universalD. Genetic code is non-overlapping |
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Answer» Correct Answer - a |
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| 362. |
Which is incorrect with reference to the transofrming principle ?A. S strain `rarr` Inject into mice `rarr` Mice dieB. R strain `rarr` Inject into mice `rarr` Mice liveC. S strain (heat killed) `rarr` Inject into mice `rarr` Mice liveD. S strain (hear killed) + R strain (live) `rarr` Inject into mice `rarr` Mice live |
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Answer» Correct Answer - D `**" "`S strain `rarr` Inject into mice `rarr` Mice die ltbr. `**" "`R strain `rarr` Inject into mice `rarr` Mice live `**" "`S strain (heat killed) `rarr` Inject into mice `rarr` Mice live `**" "`S strain (heat killed) + R strain (live) `rarr` Inject into mice `rarr` Mice die |
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| 363. |
One of the following is major requirement for DNA fingerprinting isA. Electron microscopyB. ElectrophoresisC. ELISAD. HPLC |
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Answer» Correct Answer - B Electrophoresis is major requirement for DNA finger printing. |
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| 364. |
Nucleic acids were discorvered by `:`A. Watson and CrickB. KhoranaC. WilkinsD. Miescher |
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Answer» Correct Answer - D Nucleic acids (DNA) were discovered by Miescher. |
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| 365. |
The transfer of genetic material from one bacterial cell to another bacterial cell with the help of a bacteriophage was dicovered by laderberg and Zinder. It is known asA. MutationB. transformationC. transductionD. gene flow |
| Answer» Correct Answer - C | |
| 366. |
Regulated unit of genetic material is calledA. Operator geneB. regulator geneC. operonD. promoter gene |
| Answer» Correct Answer - C | |
| 367. |
In RNA, the thymine is replaced by `:`A. adenineB. guanineC. cytosineD. Uracil |
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Answer» Correct Answer - D DNA consists of nitrogenous bases , adenine ., guanine , cytosine and thymine , whereas in RNA thymine is replaced by uracil . The other nitrogeneous bases , i.e. adenine , guanine , cytosine are present both in RNA and DNA. |
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| 368. |
A nucleotide is formed ofA. purine , pyrimidine and phosphateB. purine , sugar and phosphateC. nitrogen base , sugar and phosphateD. pyrimidine , sugar and phosphate |
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Answer» Correct Answer - C Nucleotide is the basic unit of nucleic acids (DNA and RNA) . It is composed of nucleoside nitrogeneous base + pentose sugar) and phosphate group. |
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| 369. |
The process of DNA formation from RNA is called `:`A. transversionB. transcriptionC. translationD. translocation |
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Answer» Correct Answer - B The transfer of genetic information form DNA to RNA (mRNA) is known as transcribe RNA but only one of then does it which is called as template strand. |
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| 370. |
In the coding dictionary, there are 64 codons as `:`A. 64 amino acids are to be codedB. 64 types of tRNAs are presentC. there are 44 non - sense codons and 20 sense codonsD. genetic code is triplet |
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Answer» Correct Answer - D It has been found that a sequence of 3 consecutive bases in a DNA molecule codes for one specific amino acid . So , genetic codes is a triplet code and there are 64 triplets which are called codons `(4xx4xx4x=64)` of notrogen bases for protein synthesis. |
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| 371. |
DNA replication is `:`A. conservative and discontinuousB. semi - conservative and semidiscontinuosC. semi - conservative and discontinuousD. conservative |
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Answer» Correct Answer - B DNA replication is semi- conservative that means DNA formed after replication contains one strand of its parent DNA and this was proved by Meselson and Stahl [1958]. During replication the strand formed in leading strand is continuous , while the strand formed in lagging strand is discontinuous in the small pieces (Okazaki fragments). |
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| 372. |
Genetic code consists ofA. adenine and guanineB. cytosine and uracilC. cyosine and guanineD. All of the above |
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Answer» Correct Answer - D The sequence of nitrogen bases on the mRNA which store information for linking the amino acids in a defite sequence during synthesis of proteins is called genetic code . These nitrogen bases include adenine , guanine , cytosiine and uracil |
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| 373. |
Which is correct match the phenomenon and its explanationA. Central dogma `to`RNA `to`DNA `to` Protein `to` RNAB. Reverse transcription - PCR - Many copies of DNA sequenceC. Transcription- Formation of RNA and proteinsD. RNA silencing- Use of dsRNA |
| Answer» Correct Answer - b | |
| 374. |
The term, genetic RNA refers toA. Genetic material of RNA virussesB. RNA that carries genetic messageC. RNA that helps gene regulation in lac-operonD. RNA present in mitochondria |
| Answer» Correct Answer - a | |
| 375. |
Non - genetic RNA is of`A. Two typesB. Three typesC. Only one typeD. None of these |
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Answer» Correct Answer - b b) Non-genetic RNA is 3 types mRNA, tRNA, rRNA and theya re related with synthesis of proteins. |
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| 376. |
mRNA is a polymer ofA. DeoxyribonucleosidesB. RibonucleosidesC. DeoxyribonucleotidesD. Ribonucleotides |
| Answer» Correct Answer - d | |
| 377. |
Assertion : Histones are basic proteins of major importance in packaging of eukaryotic DNA, DNA and histones comprise chromatin forming the bulk of eukaryotic chromosome . Reason : Histones are five major types `H_(1), H_(2)A, H_(2)B, H_(30` and `H_(4)`A. If both the assertion and the reason are true and the reason is a correct explanation of the assertion.B. If both the assertion and reason are true but the reason is not a correct explanation of the assetionC. If the assertion is true but the reason is falseD. If the both the assertion and reason are false |
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Answer» Correct Answer - b b) DNAwith histone octamer form a nucleosome which comprises a major part of chromatin. Histones are of 5 types. |
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| 378. |
Which of the following are the purine nucleotides ?A. Adenine and cytosineB. Guanine and thymineC. Cytosine and thymineD. Adenine and guanine |
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Answer» Correct Answer - D Adenine and guanine are the purine nucleotides. |
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| 379. |
Taylor experiment on Vicia faba (broad bean) root tips using autoradiography demonstrates thatA. DNA replication is continuousB. DNA replicates in discontinuous mannerC. chromosomes show semiconservative replicationD. DNA replicates in conservative manner |
| Answer» Correct Answer - C | |
| 380. |
What is the function of tRNA ? |
| Answer» To carry appropriate amino acids to mRNA codons. | |
| 381. |
Site for protein synthesis isA. NucleusB. CytosolC. RibosomeD. Lysosome |
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Answer» Correct Answer - C Site for protein synthesis is ribosome. |
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| 382. |
What is a codon ? |
| Answer» A base triplet on mRNA chain. | |
| 383. |
What is "A" and "B" in given diagram A. A=RNA Primer B=RNA HelicaseB. A=RNA Primer B=DNA HelicaseC. A=single strand Binding Protein B=DNA HelicaseD. A=lagging strand B=Movement of Helicase |
| Answer» Correct Answer - b | |
| 384. |
Bacteria were grown in a medium containing heavy isotope of nitrogen `(N^(15))` for many generations and all their DNA contained many heavy nitrogen only. A bacterium of this type was transferred to nomal medium and allowed to duplicate . After two divisions of heavy DNA is likely to be thatA. Only one daughter cell will have heavy DNAB. Two daughter cells have normal DNA and other two have both normal and heavy DNAC. All daughter cells have heavy DNAD. Half daughter cells have DNA and other hald have normal DNA |
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Answer» Correct Answer - b b) After two divisons, four bacterial cells are formed in which two daughter bacterial cells have normal DNA and other two have both normal and heavy DNA because DNA replicates by semiconservative method in bacteria. |
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| 385. |
If DNA replication is conservative, what woul be expected distribution of labelled DNA molecule after two generations.A. 1/4 of the molecules would be `N^(15)" "N^(15)`B. 3/4 of the molecues would be `N^(14)" "N^(14)`C. No `N^(14)" "N^(15)` molecules would be observedD. All the above statements are correct |
| Answer» Correct Answer - D | |
| 386. |
tRNA takes part inA. Transfer of genetic code to cytoplasmB. Carry amino acids to ribosomesC. Collection of RNA in ribosomeD. Copy the genetic code from DNA in nucleus |
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Answer» Correct Answer - B `**" "`mRNA function as template. `**" "`tRNA reads the genetic code and brings aa. `**" "`rRNA plays structural and catalytic role. |
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| 387. |
In Lac-operon, repressor protein binds toA. Regulator geneB. Operator geneC. Promoter geneD. Structural gene |
| Answer» Correct Answer - B | |
| 388. |
Which one is correctly matched ?A. AUG, ACG - Start or methionineB. UUA, UCA - LeucineC. GUU - AlanineD. UAG, UGA - Stop |
| Answer» Correct Answer - D | |
| 389. |
Statement A : The primary transcript produced in eukaryotic is translated without undergoing any modification or processing. Statement B: The hn-RNA in humans has exons and introns.A. If both assertion and reason are true and the reason is the correct explanation of the assertion.B. If both assertion and reason are true but reason is not the correct explanation of the assertion.C. If assertion is true but reason is false.D. If both assertion and reason are false. |
| Answer» Correct Answer - D | |
| 390. |
Find out the incorrect matchA. E.coli`-4.6xx10^(6)`bpB. Bacteriophage lambda-48502 base pairsC. haploid content of human DNA`-3.3xx10^(9)`bpD. `phixx174`-5386 base pairs |
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Answer» Correct Answer - D `phixx174` has single stranded DNA. It has 5386 nucleotides and not base pairs. |
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| 391. |
The lac operon is turned on when allolactose molecules bind toA. Promoter siteB. Operator siteC. mRNAD. Repressor protein |
| Answer» Correct Answer - d | |
| 392. |
Choose the correct pair having same meaningA. DNA fingerprinting-DNA frofilingB. Gene pool-genomeC. Codon-geneD. Cistron-triplet |
| Answer» Correct Answer - A | |
| 393. |
A heavy DNA `(N^(15)N^(15))` of Egtcoli si allowed to replicated in `N^(14)` medium for 80 minutes. What would be the proportions of light `(N^(14)-N^(14))` and hybrid densities of DNA `(N^(14)-N^(15))` molecules?A. `50:50`B. `75:25%`C. `87.5:12.5%`D. all hybride |
| Answer» Correct Answer - C | |
| 394. |
How is the first ribonucleotide different from others in the RNA chain? |
| Answer» First ribonucleotide in RNA chain is triphosphate, others are monophosphates | |
| 395. |
What changes happen during processing of RNA? |
| Answer» During RNA processing, (i) unwanted nucleotides are removed, (ii) useful regions are rejoined, (iii) certain nucleotides are added, (iv) some nucleotides are modified, and (v) folding of molecule. | |
| 396. |
Transcription Unit |
| Answer» The bases of DNA sense strand from the promotor to the terminator sites form a transcription unit. | |
| 397. |
What are auxotrophs ? |
| Answer» Mutant organisms that cannot grow in the minimal medium and need additional nutrients. | |
| 398. |
What are two functions of DNA polymerase ? |
| Answer» DNA polymerase catalyses synthesis of DNA and helps also in proof-reading. | |
| 399. |
Backbone of DNA strand is built up ofA. nitrogen base, phosphate and deoxyribose sugarB. alternate nitrogen base and phosphateC. alternate nitrogen base and deoxyribose sugarD. alternate phosphate and deoxyribose sugar |
| Answer» Correct Answer - D | |
| 400. |
Protein doess not constitute genetic material because itA. is not ubiquitousB. is a small moleculeC. does not possess ability to replicateD. does not possess diversity |
| Answer» Correct Answer - C | |