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This section includes InterviewSolutions, each offering curated multiple-choice questions to sharpen your knowledge and support exam preparation. Choose a topic below to get started.
| 251. |
The experimental system used in studies on replication of DNA isA. Escherichia coliB. Neurospora crassaC. Drosophila melanogasterD. Zea mays |
| Answer» Correct Answer - A | |
| 252. |
The anti -paralle nature of DNA refers toA. Its charged phosphated groupsB. The formation of hydrogen bonds between from opposite strandsC. The opposite direction of the two strandsD. The pairing of bases on one strands with bases on the other strands |
| Answer» Correct Answer - c | |
| 253. |
The anti -paralle nature of DNA refers toA. Its charged phosphate groupB. The formation of hydrogen bonds between bases from opposite strandsC. The opposite direction of the two strandsD. The pairing of bases on one strand with bases on the other strand. |
| Answer» Correct Answer - C | |
| 254. |
Split genes includeA. ExonsB. IntronsC. PseudoallelesD. Both A and B |
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Answer» Correct Answer - D Splite genes include exons and introns. |
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| 255. |
DNA is double helix and `:`A. Complementary and parallelB. Complamentary and antiparallelC. Without super coilsD. Always circular |
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Answer» Correct Answer - B DNA double helix is complementary and antiparallel. |
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| 256. |
The similarity between DNA and RNA is that both areA. Similar sugarsB. similar mode of replicationC. Similar pyrimidinesD. Polymers of nuleotides |
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Answer» Correct Answer - D Similarity between DNA and RNA is that both have polymers of nucleotides. |
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| 257. |
Condensation product of adenine, ribose and phosphoric acid is named as `:`A. Adenylic acidB. Adenine phosphateC. AdensosineD. None of the above |
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Answer» Correct Answer - A Condensation product of admine, ribose and phosphoric acid is adenylic acid/nucleotide. |
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| 258. |
One turn of the helix in a B- from DNA is approximatelyA. 0.34 nmB. 3.4 nmC. 3.4 ÅD. 20 nm |
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Answer» Correct Answer - B Length of one coil of B-DNA helix is 3.4 nm or 34 Å. |
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| 259. |
Nucleotide pairs present in one turn of DNA helixA. 20B. 8C. 10D. 9 |
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Answer» Correct Answer - C Nucleotide pairs present in one turn of DNA helix are 10. |
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| 260. |
The amino acid trytophan is the precursor for the synthesis ofA. Melatonin and SerotoninB. Thyroxine and TriiodothyronineC. Estorgen and ProgestreroneD. Cortisol and Cortisone |
| Answer» Correct Answer - a | |
| 261. |
DNA or RNA segment tagged with a radioative molecule is calledA. PlasmidB. VectorC. ProbeD. Clone |
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Answer» Correct Answer - c c) Probe, - 5-30 long Radioactive/Non radioactive segment DNA/RNA that is used in hybridization with DNA segment. |
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| 262. |
In DNA percentage of thymine is 20, then what is the percentage of guanine ?A. `20%`B. `40%`C. `30%`D. `60%` |
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Answer» Correct Answer - C Total DNA [100] =A +T +C +G A= 20% (given) A= T (base pairing rule) 100 =20 +20 +C +G C+G =100 -40 =60 C = G= 30 (C= G) |
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| 263. |
In E.coli during lactose metabolism, repressor binds to :A. regulator geneB. operator geneC. structural geneD. promoter gene |
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Answer» Correct Answer - B In Lac operon , the repressor protein combines with the operator gene to express its functioning. |
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| 264. |
Which of the following viruses is capable of synthesising RNA over RNA?A. Coliphage lambdaB. HIVC. `phixx174`D. TMV |
| Answer» Correct Answer - D | |
| 265. |
Repressor of operon model binds itself toA. regulator geneB. promoter geneC. structural geneD. operator gene |
| Answer» Correct Answer - D | |
| 266. |
Choose the wrong statementA. VNTR belong to a class of mini-satellite DNAB. DNA seuencers work on the principle developed by Frederick SangerC. HGP was coordinated by US Deparment of energy and the National institude of HealthD. DNA finger printing involves identifying similarities in repetitive DNA |
| Answer» Correct Answer - d | |
| 267. |
In general, which one of the following statements is wrong?A. One codon for one amino acidB. Many codons can code for one amino acidC. One codon can code for many amino acidsD. Codons are subject to poit mutations |
| Answer» Correct Answer - C | |
| 268. |
Heterogeneous nuclear RNA is converted into mRNA byA. SplicingB. CappingC. TailingD. All of the above |
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Answer» Correct Answer - D Heterogeneous nuclear RNA (hn RNA) is converted into mRNA by splicing, capping and tailing. |
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| 269. |
The technique of DNA fingerprinting relies onA. Repetitive DNAB. Mini-satellite DNAC. Both A and BD. None of the above |
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Answer» Correct Answer - C the technique of DNA finger printing relies on repetitive DNA and mini-satellite DNA. |
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| 270. |
Which of the following is not relevant to the structure of double helical DNAA. The helix makes one complete spiral turn every 3.4ÅB. The diamerter of the helix is 20ÅC. The distance between adjacent nucleotide is 3.4ÅD. Each strand of helix has a backbone made up of alternating ribose sugar and phosphate |
| Answer» Correct Answer - d | |
| 271. |
During electrolphoresis, DNA fragment would migrateA. From anode to cathodeB. From cathode to anodeC. In both directionsD. Smaller ones to anode and larger ones to cathode |
| Answer» Correct Answer - B | |
| 272. |
1.7 m double helical DNA will have base pairsA. `3.4xx10^(9)`B. `5xx10^(9)`C. `1.7xx10^(9)`D. `1.7xx10^(5)` |
| Answer» Correct Answer - B | |
| 273. |
If a lengh of DNA has 45,000 base pairs , how many complete turns will the DNA molecule takeA. 4500B. 45000C. 45D. 450 |
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Answer» Correct Answer - a a) In each turn of the double helix structrue of DNA, there are 10 base pairs each placed at a distance of 3.4`Å`. Hence, if the length of DNA has 45,000 bp, the complete turns of DNA molecule is `4,500`. |
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| 274. |
What would be the length of DNA containing 10000 base pairs?A. 68000ÅB. 34000ÅC. 10000ÅD. l m |
| Answer» Correct Answer - B | |
| 275. |
In histroy of biology , Human genome project led to the development ofA. BioinformaticsB. BiotechnologyC. BiomonitoringD. Biosystematics |
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Answer» Correct Answer - A HGP was closely associated with rapid development of a new area in biology called Bioinformatics. |
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| 276. |
The phenomenon of closely placed genes being inherited together isA. LinkageB. Crossing overC. Gene interactionD. Qualitative inheritance |
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Answer» Correct Answer - A The phenomenon of closely plced genes being inherited together is linkage. |
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| 277. |
Amount of DNA per diploid cell of man and its length is aboutA. 100 g and `1.74mxx10^(15)`B. 5.6 pg and 1.74cmC. 6.4 pg and 220 cmD. 100g and 1.74 m |
| Answer» Correct Answer - C | |
| 278. |
Central Dogma of modern genetics isA. `DNAtoRNAto`proteinB. `DNAto"protein"toRNAto`proteinC. `RNAtoDNAtoRNAto`proteinD. `RNAtoRNAtoDNAto`protein |
| Answer» Correct Answer - A | |
| 279. |
mRNA carries the genetic information from DNA to the Or Which of the following is the sita of translation of the mRNAA. ChloroplastsB. RibosomesC. MitochondriaD. Lysosome |
| Answer» Correct Answer - b | |
| 280. |
Coding segment of DNA contains CAC. Which amino acid is picked up during ranslation ?A. LeucineB. Glutamic acidC. ValineD. Methionine |
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Answer» Correct Answer - C `{:("Coding strand",CAC),("Template strand",GTG),(,darr" transcription"),(mRNA,CUC" (Codon)"),(,darr" Codes for"),(,"Leucine"):}` |
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| 281. |
Two or more codons coding for one amino acidA. Non -ambiguousB. Degeneracy of codonC. Non - overlapping of codonD. Non- sense codon |
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Answer» Correct Answer - b b) When more than one codon may specifiy the same amino acid, this is called degeneracy of codon. Except for tryptophan and methionine all other 18 amino acids have more than one codon. |
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| 282. |
Triplet UUC codes forA. LeucineB. MethionineC. PhenylalanineD. Glycine |
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Answer» Correct Answer - C Triplet UUU codes for phenylalanine. |
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| 283. |
Nonsense codon takes part inA. Terminating message of gene controlled protein synthesisB. Formation of unspecified amino acidsC. Conversion of sense DNA into non-sence oneD. Releasing tRNA from polypeptide chain |
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Answer» Correct Answer - A Nonsense codon (stop codon) takes part in terminating message of gene controlled protein synthesis. |
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| 284. |
Select correct statement about protein synthesis.A. Translation begins when mRNA attaches to small subunit of ribosome.B. Peptidase catalyses formation of peptide bond.C. UTRs are present between strat and stop codons.D. At the end of translation, release factor binds to intiation codon. |
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Answer» Correct Answer - A `**" "`The cellular factory responsible for synthesis proteins is the ribsome. The ribosome consists of structural RNAs and about 80 different proteins. `**" "`In its inactive state, it exists as two subunits, a large subunit and a small subunit. `**" "`When the small subunit encounters an mRNA, the process of translation of the mRNA to protein begins. |
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| 285. |
Which codon does not have tRNA ?A. Start codonB. Stop codonC. AUGD. GGG |
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Answer» Correct Answer - B `**" "`t-RNAs are specific for each amino acid. There are 20 types of t-RNA for 20 types of aa. `**" "`For initiation, there is another specific t-RNA that is refferred to as initiator t-RNA. There are no t-RNAs for stop codons. |
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| 286. |
In DNA when AGCT occurs , their association is as per which of the following pairs ?A. ACGTB. AGCTC. ATGCD. All of these |
| Answer» In DNA AGCT is associated with pair ATGC because in a DNA molecule , the purine adenine in either chain is associated with the pyrimidine thymidine on the other . Similarly , purine guanine in either chain is associated with pyrimidine cytosine on the other. | |
| 287. |
Which enzyme/s will be produced in a cell in which there is a nonsese mutation in the lac Y geneA. `beta` - galactosidaseB. Lactose permeaseC. TransacetylaseD. Lactose permease and transacetylase |
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Answer» Correct Answer - A `beta` - galactosidase is a structural gene , which carry codes for the synthesis of protein Multation in the lac Y gene of E. coli needs residues of cytoplasmic enzyme `beta` - galactosidase . Lactose permease is a membrane protein , which is a major facilitator superfamily. Transacetylase is an enzyme transferring acetyl groups from one compound to another. |
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| 288. |
Transformation was discovered byA. Meselson and StahlB. Hershey and ChaseC. GriffithD. Wastson and Crick |
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Answer» Correct Answer - C Transformation was discovered by F Griffith [1928] . He isolated the DNA as genetic material that inherit the genetic information between two generations by using two strain of Pneumococcus bacteria which infect mice . i.e. type III S(smooth) and type II R (rough) strain. |
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| 289. |
The diagram shows an important concept in the genetic implicatio of DNA. Fill in the blanks A to C. A. A-transcription, B-translation, C-Francis crickB. A-translation, B-extension, C-Rosalind franklinC. A-transcription, B-replication, C-James watsonD. A-translation, B-transcription, C_Erevin chargaff |
| Answer» Correct Answer - A | |
| 290. |
The diagram shows an important concept in the genetic implicatio of DNA. Fill in the blanks A to C. A. A-Translation B -Thmscription C -Frevin ChargaffB. A -Transcription B -Translation C -Francis CrickC. A -Trans1ation B - Extension C - Rosalind FranklinD. A - Transcription B - Replication C - James Watson |
| Answer» Correct Answer - B | |
| 291. |
DNA fingerprinting refers toA. Techniques used for molecular analysis of different specimens of DNAB. Techniques used for identification of fingerprints of individualsC. Molecular analysis of profile of DNA samplesD. Analysis of DNA samples using imprinting devices |
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Answer» Correct Answer - c c) DNA fingerprinting is a modern technique that compares sets of DNA by locating identical sequences of nucleotides, often for purposes of forensic identification. |
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| 292. |
One gene one polypeptide theory can be explained by:-A. alkaptonuriaB. phenylketonuriaC. sickle cel anaemiaD. all of these |
| Answer» Correct Answer - D | |
| 293. |
Value (constant value) of Dna refers toA. total amount of DNA per somatic cellB. total amount of DNA/base pairs per genomeC. amount of DNA in autosomesD. amount of DNA which is heritable and present in autosomes |
| Answer» Correct Answer - B | |
| 294. |
Template refers toA. The physical basis of heredityB. unit of DNA having coded information and act as a model from which information is collected by mRNAC. a genetic element which may or may not be present in a cell associated with the chromosomesD. a complete set of chromosomes which is transferred to the gametes |
| Answer» Correct Answer - B | |
| 295. |
Which one of the following has minimum life span?A. mRNAB. rRNAC. tRNAD. DNA |
| Answer» Correct Answer - A | |
| 296. |
The codons causing chain termination (stop codons) areA. TAG,TAA, TGAB. GAT,AAT,AGTC. AGT,TAG UGAD. UAG,UGA,UAA |
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Answer» Correct Answer - d d) Termination codons are also known as the non-sense codons or stop codons because they stop the process of protein synthesis being not coded for amino acid during translation. |
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| 297. |
Which antiotic inhibits interaction between t RNA and m RNA during bacterial synthesisA. StreptomycinB. TetracylineC. ErythromycinD. Neomycin |
| Answer» Correct Answer - d | |
| 298. |
DNA is acidic due toA. sugarB. Phosphoric acidC. PurineD. Pyrimidine |
| Answer» Correct Answer - b | |
| 299. |
RNA in not found inA. ChromosomeB. PlasmmalemmaC. NucleolusD. Ribosome |
| Answer» Correct Answer - b | |
| 300. |
Here are some correct and some wrong statements. Correct only those statements which are wrong: (a) The genetic code is universal. (b) The genetic code is ambiguous. (c) The genetic code is regenerate. (d) Transfer RNA (tRNA) carry amino acids to mRNA codons and used again and again in transcription. (e) UAA, UAG and UGA are terminator codon. (f) Lac operon consists of regulatory genes, operator gene, structural and promoter gene. |
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Answer» (a) Correct. (b) The genetic code is non-ambiguous. (c) The genetic code is degenerate. (d) Transfer RNA (tRNA) can amino acids to mRNA codons and used again and again in translation. (e) Correct. (f) Correct. |
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