756 + Interview Questions in MOLECULAR-BASIS-OF-INHERITANCE IN GENERAL AWARENESS Page 9 InterviewSolution

401.	Genetic material should beA. ubiquitousB. able to permit diversityC. capable of replicationD. All the above
Answer» Correct Answer - D

Discussion

402.	Fill in the blanks VNTRs is an abbreviation of....
Answer» Variable number tandem repeats.

Discussion

403.	Give one word. One codon codes for only one amino acid. The genetic code is ....
Answer» Correct Answer - nonambiguous.

Discussion

404.	True/False Type Question. F. Griffith conducted experiment with bacteriopbages.
Answer» Correct Answer - False.

Discussion

405.	True/False Type Question. The structural gene in prokaryotes is polyclstronic.
Answer» Correct Answer - True.

Discussion

406.	Pleitropy is a condition in which a single geneA. Controls only one phenotypeB. Controls more than one phenotypeC. Does not control any phenotypeD. None of these
Answer» Correct Answer - b

Discussion

407.	What is the correct sequence of processes involved in central dogmaA. Replication ,transcription , translationB. Replication, translation, transcriptionC. Translation ,replication, transcriptionD. Transcription , replication, translation
Answer» Correct Answer - a

Discussion

408.	Who was awarded Noble prize for the synthesis of an artificial geneA. Hargovind KhoranaB. M. S. SwaminathanC. B. P palD. P .Maheshwari
Answer» Correct Answer - a

Discussion

409.	Who was awarded Noble prize for synthesis of RNA in 1959A. S. OchoaB. A. KornbergC. H. KhoranaD. Nirenberg
Answer» Correct Answer - a c) Nobel prize for artificial synthesis of RNA was given to S. Oschoa (1959).

Discussion

410.	What is the best way to test the relatedness of two species.A. RNA and proteinsB. DNA & proteinsC. Antibodies and transposonsD. None of these
Answer» Correct Answer - b

Discussion

411.	Which one represents serine ?A. CUU, CUC, CUA and CUGB. UAU, UAC, UGU and UGCC. UCU, UCC, UCA and UCGD. UGU. UGC. UGA and UAG
Answer» Correct Answer - C

Discussion

412.	How many effective codons are there for the synthesis of twenty amino acidsA. 64B. 32C. 60D. 61
Answer» Correct Answer - d d) out of 64 codons, 61 codons code for amino acids and the rest three UAG, UAA and UGA are stop codons(i.e. do not specify any amino acids)

Discussion

413.	How many effective codons are there for the synthesis of twenty amino acids ?A. 64B. 32C. 60D. 61
Answer» Correct Answer - D

Discussion

414.	Assertion : In stem, pericycle take active part in secondary growth. Reason : In dicots, pericycle has the capacity to produce lateral roots.A. If both assertion and reason are true and the reason is a correct explanation of the assertion.B. If both assertion and reason are true and the reason is not a correct explanation of the assertion.C. If the assertion is true but reason is false.D. If both assertion and reason are false.
Answer» Correct Answer - C

Discussion

415.	Match the codons given in column I with their respective amino acids given in column II and choose the correct answer. A. a-III, b-IV, c-I, d-V, e-IIB. a-III, b-I, c-IV, d-V, e-IIC. a-III, b-IV, c-V, d-I, e-IID. a-II, b-IV, c-I, d-V, e-III
Answer» Correct Answer - A

Discussion

416.	The given figure shows the structure of ne with their parts labelled as A, B & C. Identify A, B and C. A. A-DNA, `B-H_(1)` histone, C - Histone octamerB. `A-H_(1)` histone, B-DNA, C - Histone octamerC. A - Histone octamer, B-RNA, `C- H_(1)` histoneD. A - RNA, `B-H_(1)` histone, C - Histone octamer.
Answer» Correct Answer - A

Discussion

417.	Match the items given in column I with appropriate items (o ne or more) of column II : `{:(,"Column I"," Column II"),(,"(i) m- RNA ", "(a) UAA"),(,"(ii) Initition condon ","(b) Beadle and Tatum"),(,"(iii) Termination codon","(c) AUG"),(,"(iv) Anticodon","(d) Hetergoeneous nuclear RNA (hn RNA)"),(,"(v) One gene one enzyme hypothesis","(e) GUG"),(,"(vi) Semiconservative mode of DNA replication","(f) UAG"),(,,"(g) t-RNA"),(,,"(h) Meselson and Stahl"):}`
Answer» (i) d (ii) c, e (iii) a, f (iv) g (v) b (vi) h

Discussion

418.	(i) Name the enzyme that catalyses the trancription of hnRNA. (ii) Why does the hnRNA need to undergo changes? List the changes hnRNA undergoes and where in the cell such changes take place?
Answer» (i) RNA polymerase II

Discussion

419.	Which one the following is common is to both prokaryotes and eukaryotesA. Genetic codeB. E.R.C. HistonesD. Mitotic spindle
Answer» Correct Answer - A Genetic code are common to both prokaryotes and eukaryotes.

Discussion

420.	Find out the wrong statement about heterochromatin.A. It is densely packed.B. It stains dark.C. It is transcriptionally activeD. It is late replicating
Answer» Correct Answer - c (c) : A typical nucleosome contains 200 bp of DNA helix. Nucleosomes constitute the repeating unit of a structure in nucleus called chromatin. Chromatin is held over a scaffold of non -histone chromosomal (or NHC) proteins. At some places chromatin is densely packed to form darkly stainined heterochromatin. At other places chromatin is loosely packed. It is called euchromatin. It is transcriptionally active chromatin whereas heterrochromatin is transcriptionally active chromatin whereas heterochromatin is transcriptionally inactive and late replicating or heteropycnotic.

Discussion

421.	Read the following satements and select the correct option. Loosely packed and light stained region of chromation are called as heterochromatin. (ii) Densely packed and dark stained region of chromatin are called as euchromatin. (iii) A typical nucleosome contains 200 bp of DNA helix.A. Statements (i) and (ii) are true , but statement (iii) is false.B. Statement (i) and (ii) are false, but statement (iii) is true.C. Statement (ii) and (iii) are true , but statement (i) is false.D. All the statements are true.
Answer» Correct Answer - b (b) : A typical nucleosome contains 200 bp of DNA helix. Nucleosomes constitute the repeating unit of a structure in nucleus called chromatin. Chromatin is held over a scaffold of non -histone chromosomal (or NHC) proteins. At some places chromatin is densely packed to form darkly stainined heterochromatin. At other places chromatin is loosely packed. It is called euchromatin. It is transcriptionally active chromatin whereas heterrochromatin is transcriptionally active chromatin whereas heterochromatin is transcriptionally inactive and late replicating or heteropycnotic.

Discussion

422.	Heterochromatin region isA. Genetically more activeB. Genetically less activeC. Loosely coiled regionD. Lightly coloured region
Answer» Correct Answer - B Heterochromatic region is genetically lase active.

Discussion

423.	DNA duplex showsA. Right handed coiling and parallelB. Right handed coiling and antiparallelC. Left handed coiling and antiparallelD. Left handed coiling and parallel
Answer» Correct Answer - B DNA duplex shows right handed coiling and antiparallel.

Discussion

424.	`DNA` replication requiresA. DNA polymeraseB. RNA polymerase and translocaseC. DNA ligaseD. DNA polymerase and DNA ligase
Answer» Correct Answer - D DNA replication requires DNA polymerase and DNA ligase.

Discussion

425.	mRNA is a polymer ofA. RibonucleotidesB. DeoxyribonucleotidesC. RibonucleosidesD. Deoxyribonucleosides
Answer» Correct Answer - A mRNA is polymer of ribonucleotides.

Discussion

426.	mRNA directs building of protein through a sequence ofA. ExonsB. IntronsC. CodonsD. Anti codons
Answer» Correct Answer - C

Discussion

427.	mRNA direct the building of proteins through a sequience ofA. ExonsB. IntronsC. CodonsD. Anticodons
Answer» Correct Answer - c

Discussion

428.	mRNA directs building of protein through a sequence ofA. IntronsB. ExonsC. AnticodonsD. Codons
Answer» Correct Answer - D mRNA directs building of protein through a sequence of codons.

Discussion

429.	Name the RNA that carries information about the sequence of amino acids in a polypeptide.
Answer» Correct Answer - mRNA.

Discussion

430.	3-D structure of RNA is calledA. Clover leaf modelB. Hair pin modelC. Helical modelD. Plate model
Answer» Correct Answer - a

Discussion

431.	In agarose gel electrophoresis, DNA molecules are separated on the basic of theirA. ChargeB. ConcentrationC. pHD. Size
Answer» Correct Answer - d c) The arrangement of compounds in ascending order according to their molecular weight is AMP, ADP, ATP, RNA, DNA

Discussion

432.	In which of the following combinations, the compouns in ascending order based on their molecular weights are arranged.A. DNA, RNA, AMP, ADP, ATPB. DNA, RNA, ATP, ADP, AMPC. AMP, ATP, RNA, DNAD. AMP, ATP, ADP, DNA, RNA
Answer» Correct Answer - c

Discussion

433.	Which is the site of translation of mRNA ?A. NucleusB. NucleolusC. Golgi bodyD. Ribosomes
Answer» Correct Answer - D Ribosomes is the site of translation (protein synthesis) of mRNA.

Discussion

434.	Sequence of amino acids in a polypeptide is determined byA. rRNAB. mRNAC. tRNAD. snRNA
Answer» Correct Answer - B Sequence of amino acids in a polypeptide is determined by mRNA.

Discussion

435.	Which one the following statements are correct ? (i) RNA polymerase I transcribes rRNAs (ii) RNA polymerase II transcribes snRNAs (iii) RNA polymerase III transcribes hnRNA (iv) RNA polymerase II transcribes hnRNAA. (i) and (ii) are correctB. (i) and (iii) are correctC. (i), (ii) and (iv) are correctD. (i) and (iv) are correct
Answer» Correct Answer - e

Discussion

436.	Initiation of DNA strand synthesis is performed byA. DNA polymerase 1B. DNA HelicaseC. DNA PrimaseD. DNA Topoisomerase
Answer» Correct Answer - c

Discussion

437.	The movement of a gene from one linkage group to an other is calledA. TranslocationB. Crossing overC. InversionD. Duplication
Answer» Correct Answer - A The movement of a gene from one linkage group of another is called translocation.

Discussion

438.	Satellite DNA is important because itA. Shows high degree of polymorphism in population and also the same degree of polymorphism in an individual, which is heritable from parents to children.B. Does not code for proteins and is same in all members of the population.C. Codes for anzymes needed for DNA replication.D. Codes for proteins needed in cell cycle.
Answer» Correct Answer - A Satellite DNA is important because it shows high degree of polymorphism in population and also the same degree of polymorphism in an individual, which is heritable from parents to children.

Discussion

439.	Satellite DNA is important because itA. Shows high degree of polymorphism in population and also the same degree of polymorphism in an individual, which is heritable from parents to childrenB. Does not code for proteins and is same in all members of the populationC. Codes for enzymes needed for DNA replicationD. Codes for protein needed in cell cycle
Answer» Correct Answer - a

Discussion

440.	Satellite DNA is important because itA. codes for proteins needed in cell cycleB. shows high degree of polymorphism in population and also the same degree of polymorphism in an individual, which is heritable from parents to children.C. does not code for proteins and is same in all members of the populationD. codes for enzymes needed for DNA replication.
Answer» Correct Answer - B

Discussion

441.	Who proposed the central dogma ?A. Watson and CrickB. Bradle and TatumC. KlugD. Crick
Answer» Correct Answer - D Crick proposed central dogma.

Discussion

442.	Reverse transcriptase is `:`A. RNA dependent RNA polymeraseB. DNA dependent RNA polymeraseC. DNA dependent DNA polymeraseD. RNA dependent DNA polymerase
Answer» Correct Answer - D Reverse transcriotase is RNA dependent DNA polymerse.

Discussion

443.	Gene does not produceA. mRNAB. SugarC. PolypeptideD. Enzyme
Answer» Correct Answer - B Gene does not produce sugar.

Discussion

444.	Okazaki is known for bis contribution to the understanding ofA. transcriptionB. translationC. DNA replicationD. mutation
Answer» Correct Answer - C

Discussion

445.	Okazaki is known for his contribution to the understanding ofA. TranscriptionB. TranslationC. MutationD. DNA replication
Answer» Correct Answer - D Okazaki is known for his contribution to the understanding of DNA replication.

Discussion

446.	Which one of the following pairs is correctly matchedA. Ribosomal RNA `" "` Carries amino acids to the side of protein sysnthesisB. Transcription `" "` Process by which protein is sysnthesizedC. Translation `" "` Process by which m-RNA carries the information from the nucleus to ribosomesD. Anticodon `" "` Site of a t-RNA molecules hydrogen bond that binds to the m-RNA molecule
Answer» Correct Answer - d

Discussion

447.	Which one of the following is the starter codon ?A. UAAB. UAGC. AUGD. UGA
Answer» Correct Answer - C AUG is the starter codon.

Discussion

448.	Which one of the following is the starter codon ?A. UGAB. UAAC. UAGD. AUG
Answer» Correct Answer - D AUG is the start codon . It also codes for amino acid called methionine which is the first amino acid in a polypeptide chain . UAA , UAG and UGA are stop codons and are meant for termination of polypeptide chain during protein synthesis.

Discussion

449.	a) Explain the process of DNA replication with the help of a schematic diagram. b) In which phase of the cell cycle does replication occur in Eukaryotes? What would happen if cell-division is not followed after DNA replication?
Answer» S phase, polyploidy.

Discussion

450.	How is the translation of mRNA terminated ? Explain.
Answer» The protein synthesizing complex (i.e., ribosome attached with mRNA) moves from codon to codon along the mRNA. Specific amino acids are added one by one and translated into polypeptide sequence as dictated by DNA via messenger RNA. At the end, a release factor binds to the stop cadon, terminating translation and releasing the complete polypetide from the protein synthesizing complex.

Discussion

Explore topic-wise InterviewSolutions in .

Genetic material should beA. ubiquitousB. able to permit diversityC. capable of replicationD. All the above

Fill in the blanks VNTRs is an abbreviation of....

Give one word. One codon codes for only one amino acid. The genetic code is ....

True/False Type Question. F. Griffith conducted experiment with bacteriopbages.

True/False Type Question. The structural gene in prokaryotes is polyclstronic.

Pleitropy is a condition in which a single geneA. Controls only one phenotypeB. Controls more than one phenotypeC. Does not control any phenotypeD. None of these

What is the correct sequence of processes involved in central dogmaA. Replication ,transcription , translationB. Replication, translation, transcriptionC. Translation ,replication, transcriptionD. Transcription , replication, translation

Who was awarded Noble prize for the synthesis of an artificial geneA. Hargovind KhoranaB. M. S. SwaminathanC. B. P palD. P .Maheshwari

Who was awarded Noble prize for synthesis of RNA in 1959A. S. OchoaB. A. KornbergC. H. KhoranaD. Nirenberg

What is the best way to test the relatedness of two species.A. RNA and proteinsB. DNA & proteinsC. Antibodies and transposonsD. None of these

Which one represents serine ?A. CUU, CUC, CUA and CUGB. UAU, UAC, UGU and UGCC. UCU, UCC, UCA and UCGD. UGU. UGC. UGA and UAG

How many effective codons are there for the synthesis of twenty amino acidsA. 64B. 32C. 60D. 61

How many effective codons are there for the synthesis of twenty amino acids ?A. 64B. 32C. 60D. 61

Match the codons given in column I with their respective amino acids given in column II and choose the correct answer. A. a-III, b-IV, c-I, d-V, e-IIB. a-III, b-I, c-IV, d-V, e-IIC. a-III, b-IV, c-V, d-I, e-IID. a-II, b-IV, c-I, d-V, e-III

The given figure shows the structure of ne with their parts labelled as A, B & C. Identify A, B and C. A. A-DNA, `B-H_(1)` histone, C - Histone octamerB. `A-H_(1)` histone, B-DNA, C - Histone octamerC. A - Histone octamer, B-RNA, `C- H_(1)` histoneD. A - RNA, `B-H_(1)` histone, C - Histone octamer.

(i) Name the enzyme that catalyses the trancription of hnRNA. (ii) Why does the hnRNA need to undergo changes? List the changes hnRNA undergoes and where in the cell such changes take place?

Which one the following is common is to both prokaryotes and eukaryotesA. Genetic codeB. E.R.C. HistonesD. Mitotic spindle

Find out the wrong statement about heterochromatin.A. It is densely packed.B. It stains dark.C. It is transcriptionally activeD. It is late replicating

Heterochromatin region isA. Genetically more activeB. Genetically less activeC. Loosely coiled regionD. Lightly coloured region

DNA duplex showsA. Right handed coiling and parallelB. Right handed coiling and antiparallelC. Left handed coiling and antiparallelD. Left handed coiling and parallel

`DNA` replication requiresA. DNA polymeraseB. RNA polymerase and translocaseC. DNA ligaseD. DNA polymerase and DNA ligase

mRNA is a polymer ofA. RibonucleotidesB. DeoxyribonucleotidesC. RibonucleosidesD. Deoxyribonucleosides

mRNA directs building of protein through a sequence ofA. ExonsB. IntronsC. CodonsD. Anti codons

mRNA direct the building of proteins through a sequience ofA. ExonsB. IntronsC. CodonsD. Anticodons

mRNA directs building of protein through a sequence ofA. IntronsB. ExonsC. AnticodonsD. Codons

Name the RNA that carries information about the sequence of amino acids in a polypeptide.

3-D structure of RNA is calledA. Clover leaf modelB. Hair pin modelC. Helical modelD. Plate model

In agarose gel electrophoresis, DNA molecules are separated on the basic of theirA. ChargeB. ConcentrationC. pHD. Size

In which of the following combinations, the compouns in ascending order based on their molecular weights are arranged.A. DNA, RNA, AMP, ADP, ATPB. DNA, RNA, ATP, ADP, AMPC. AMP, ATP, RNA, DNAD. AMP, ATP, ADP, DNA, RNA

Which is the site of translation of mRNA ?A. NucleusB. NucleolusC. Golgi bodyD. Ribosomes

Sequence of amino acids in a polypeptide is determined byA. rRNAB. mRNAC. tRNAD. snRNA

Initiation of DNA strand synthesis is performed byA. DNA polymerase 1B. DNA HelicaseC. DNA PrimaseD. DNA Topoisomerase

The movement of a gene from one linkage group to an other is calledA. TranslocationB. Crossing overC. InversionD. Duplication

Who proposed the central dogma ?A. Watson and CrickB. Bradle and TatumC. KlugD. Crick

Reverse transcriptase is `:`A. RNA dependent RNA polymeraseB. DNA dependent RNA polymeraseC. DNA dependent DNA polymeraseD. RNA dependent DNA polymerase

Gene does not produceA. mRNAB. SugarC. PolypeptideD. Enzyme

Okazaki is known for bis contribution to the understanding ofA. transcriptionB. translationC. DNA replicationD. mutation

Okazaki is known for his contribution to the understanding ofA. TranscriptionB. TranslationC. MutationD. DNA replication

Which one of the following is the starter codon ?A. UAAB. UAGC. AUGD. UGA

Which one of the following is the starter codon ?A. UGAB. UAAC. UAGD. AUG

a) Explain the process of DNA replication with the help of a schematic diagram. b) In which phase of the cell cycle does replication occur in Eukaryotes? What would happen if cell-division is not followed after DNA replication?

How is the translation of mRNA terminated ? Explain.