756 + Interview Questions in MOLECULAR-BASIS-OF-INHERITANCE IN GENERAL AWARENESS Page 14 InterviewSolution

651.	The human chromoses scientists had no contribution in the development of the double helix model for the structure of DNAA. Chromosome 21 and YB. Chromosome 1 and XC. Chromosome 1 and YD. Chromosome X and Y
Answer» Correct Answer - c

Discussion

652.	Select the correct statement regarding protein synthesis `:`A. When the small subunit of the ribosome encounters an `m RNA` the process of traslation beginsB. Peptidase catalyes the formation of peptide bondC. `UTR_(s)` are present between the codon binds to the initation codonD. The comleted polypeptide is stored in the ribosome and relseased when required
Answer» Correct Answer - a

Discussion

653.	One strand of DNA (non template) has base sequence CAG, TCG, GAT. What will be the sequence of bases in m-RNAA. AGC,CTA, CTAB. GTA,AGC,CTCC. CAG,UCG,GAUD. GAC,TAG, CTA
Answer» Correct Answer - c c) The non-template strand has same sequence as in m-RNA but thymine is replaced by uracil here.

Discussion

654.	The double helix model pf Watson and Crick is known asA. C- DNAB. B-DNAC. Z-DNAD. D- DNA
Answer» Correct Answer - b b) B-DNA is the right handed coiled and normal type of DNA.

Discussion

655.	DNA template sequence of CTGATAGC is transcribed over mRNA asA. GUCTUTCGB. GACUAUCGC. GAUTATUGD. UACTATCU
Answer» Correct Answer - B During transcription complementary mRNA is formed on DNA template in which T is replaced by U. So , the sequence will be GACUAUCG.

Discussion

656.	Assertion : The tRNA molecules posses anticondons. Reason It needs the message in form of codon.A. If both the assertion and the reason are true and the reason is a correct explanation of the assertion.B. If both the assertion and reason are true but the reason is not a correct explanation of the assetionC. If the assertion is true but the reason is falseD. If the both the assertion and reason are false
Answer» Correct Answer - b b) tRNA has anticodons which read the message expessed in the form of codons in mRNA and occupy a specific place on mRNA. tRNA also recognises the amino acids.

Discussion

657.	Which of the following codon has no tRNAA. UAAB. UAUC. UGUD. UGC
Answer» Correct Answer - a

Discussion

658.	Which property of DNA double helix led Watson and Crick to hypothesise semiconservative mode of DNA replication? Explain.
Answer» Watson and Crick suggested that the two strands of double helix DNA molecule uncoil and separate and each of the two strands serves as a template for the synthesis of a new (complementary) strand alongside it. The template (i.e., parental strand) and its complement (i.e., the daughter strand) then fonn a new DNA double strand, identical to the original DNA molecule. The sequence of bases which should be present in the new strands can be easily predicted because these would be complementary to the bases present in the old strands. A will pair with T, T with A, C with G and G with C. Thus two daughter DNA molecules are formed from the parent DNA molecule and these are identical to the parent molecule. Since each daughter DNA molecule consists of one old (parental) strand and one new strand, this mode of replication is said to be semiconservative (i.e., the new DNA molecule has conserved half of the parent molecule).

Discussion

659.	Which one is not transcribed by DNA ?A. ExonsB. IntronsC. DNAD. tRNA
Answer» Correct Answer - C DNA is not transcribed by DNA (DNA is replicated).

Discussion

660.	Study the following tRNA molecule related with anti codon pairing with respective condons. Which types of tRNA is impossible A. T 1 and T2B. T1, T2 and T3C. T1 and T4D. T3, T4 and T5
Answer» Correct Answer - d

Discussion

661.	Watson and Crick are known for their discovvery that DNAA. Is a single stranded helixB. Contains deoxyribose onlyC. Is a double stranded helixD. Synthesizes rRNA
Answer» Correct Answer - c c) according to Watson-Crick model, the DNA molecule consists of two long, parallel chains which are spirally coild around a common axis in a regualr manner to form a double helix.

Discussion

662.	In eukaryotic cell transcription, RNA splicing and RNA capping take place inside the OR Messenger RNA is produced inA. NucleusB. RibosomesC. E.RD. Dictyosomes
Answer» Correct Answer - A In eukaryotic cell, transcription, RNA splicing and RNA capping take place inside nucleus.

Discussion

663.	It ha s not escaped our notice t hat the specific pairing we have postulated immediately suggests a possible copying mechanism for genetic material. This is written byA. Meselson and StahlB. rchibold GarrodC. Secero OchoaD. Watson and Crick
Answer» Correct Answer - d

Discussion

664.	Assertion. DNA is more stable while RNA is more reactive. Reason. DNA was first discovered by Watson and Crick (1953).A. If both A and R are true and R is the correct explanation of A.B. If both A and R are true but R is not the correct explanation of A.C. If A is true but R is false.D. If both A and R are false.
Answer» Correct Answer - C

Discussion

665.	In many cells ribosomes occur in chains along messenger RNA. What is the advantage of this arrangement as compared to a situation in which ribosomes occur singly?A. A greater variety of polypeptides can be producedB. Polypeptides can be produced more rapidlyC. Fewer RNA molecules are used in protein synthesisD. The probability of gene mutation occurring is less
Answer» Correct Answer - B

Discussion

666.	The process of copying genetic information from one strand of DNA to RNA is termed as ________ .A. replicationB. transcriptionC. translationD. reverse transcription
Answer» Correct Answer - b (b) : The process of copying genetic information from one strand of the DNA into RNA is termed as transcription. Unlike the process of replication, which once sets in , the total DNA of an organism gets duplicated , in transcription only a segment of DNA and only one of the strands is copied into RNA.

Discussion

667.	Assertion : DNA is perferred over RNA for storage of genetic information. Reason : DNA is more stable than RNA.A. If both assertion and reason are true and the reason is the correct explanation of the assertion.B. If both assertion and reason are true but reason is not the correct explanation of the assertion.C. If assertion is true but reason is false.D. If both assertion and reason are false.
Answer» Correct Answer - A Both RNA and DNA can function as genetic material, but DNA being more stable is perferred for storage of genetic information. For the transmission of genetic information, RNA is better.

Discussion

668.	RNA can acts as a. Genetic material b. Messenger c. Adapter molecule d. Structural molecule e. Catalytic moleculeA. b, c and eB. a, d and eC. a, b and cD. a, b, c, d and e
Answer» Correct Answer - D RNA through it also acts as a genetic material in some viruses, mostly functions as a messenger, RNA has additional roles as well. It functions as adapter, structural, and in some cases as a catalytic molecule.

Discussion

669.	Assertion. RNA was the first genetic material. Reason. DNA has evolved from RNA by chemical modifications.A. If both A and R are true and R is the correct explanation of A.B. If both A and R are true but R is not the correct explanation of A.C. If A is true but R is false.D. If both A and R are false.
Answer» Correct Answer - B

Discussion

670.	RNA is the genetic material inA. prokaryotesB. eukaryotesC. Tobacco Mosaic Virus (TMV)D. E.coli.
Answer» Correct Answer - c (c)

Discussion

671.	Which of the following statement are incorrect ? (i)RNA act as a genetic material as well as a catalyst. (ii)RNA is more stable than DNA (iii)RNA has evolved from DNAA. (i) and (iii) onlyB. (ii) and (iii) onlyC. (i), (ii) and (iii)D. (i) and (ii) only
Answer» Correct Answer - b (b) : Evidences suggest that essential life processes such as metabolism, splicing , translation, etc. evolved around RNA . RNA used to act as a genetic material as well as a catalyst and being a catalyst it was reactive and hence unstable. Therefore, DNA has evolved from RNA with chemical modifications.

Discussion

672.	Assertion : For the transmission of genetic information, RNA is better than DNA. Reason : RNA was the First genetic material.A. If both assertion and reason are true and the reason is the correct explanation of the assertion.B. If both assertion and reason are true but reason is not the correct explanation of the assertion.C. If assertion is true but reason is false.D. If both assertion and reason are false.
Answer» Correct Answer - B `` For the transmission of genetic information, RNA is better than DNA. `` RNA was the first genetic material.

Discussion

673.	RNA acts as genetic material inA. TMVB. OQ bacteriophageC. HIVD. All of the above
Answer» Correct Answer - D [i]ssRNA : TMV, Polio cirus, HIV (Retrovirus), mumps virus, measles virus, Rabies virus, influenza virus, Papaya mosaic virus, QB bacteriophage. [ii] dsRNA : Reo virus, Rice dwarf virus and Wound tumour virus.

Discussion

674.	Which is incorrect about Hershey and Chase experiment ?A. Viruses grown in the presence of radioactive phosphorus contained radioactive protein but not radioactive DNAB. Viruses grown on radioactive sulfur contained radioactive DNA but not radioactive proteinC. Both A and BD. None of the above
Answer» Correct Answer - C `" "`Viruses grown in the presence of radioactive phosphorus contained radiactive DNA but not radioactive protein because DNA contains phosphorus but protein does not. `" "`Similarly, viruses grown on radioactive sulfur contained radiactive protein but not radiactive DNA because DNA does not contain sulfur.

Discussion

675.	(a) Mention two events in which DNA is unzipped. (b) Predict the consequences when both the template and the coding strands of a DNA segement participate in transcription process ?
Answer» (a) (i) Replication (ii) Transcription (b) In such a case, transcribed two RNA molecules will coil with each other and the total RNA transcribed will be non-functional.

Discussion

676.	Explain Hershey-Chase experiment. What was proved through this experiment ?
Answer» Figure 6.3 to show that DNA is the hereditary material in the bacteriophage `T_(2).`

Discussion

677.	Jacob and Monod won Nobel Prize for their work onA. Operon modelB. Structure of geneC. Genetic diseasesD. Function of gene
Answer» Correct Answer - A Jacob and Monad won Nobel Prize (1965) for their work on Operon model.

Discussion

678.	Ribosomal RNA is synthesised inA. lysosmesB. nucleolusC. nucleoplasmD. ribosomes
Answer» Correct Answer - B Nucleolus is the centre for synthesis of ribosomal RNA (rRNA). Ribosomal proteins migrate to the nucleolus from their assembly sites in the cytoplasm ans are packaged into ribonucleoproteins. These return to the cytoplasm where they become mature ribosome particles.

Discussion

679.	Who synthesised the first artificial gene ?A. MorgenB. NirenbergC. KhoranaD. Mendel
Answer» Correct Answer - C Khorana (1972) synthesised the first artificial gene.

Discussion

680.	A mutation at one base of the first codon of a gene produces a non-functional protein. Such a mutation is referred asA. Nonsense mutationB. Reverse mutationC. Frame shift mutationD. Mis-sence mutation
Answer» Correct Answer - D Types of point mutation : `" "`Non-sence mutation : In this, mutation stops protein synthesis due to formation of non-sence or stop codon. E.g. : `U UA rarr UA A`. `" "`Mis-sence mutation : In this, mutation changes the codon that produces different amino acid e.g. : `U UA rarr U U U`. `**" "`Same sence mutation : It is silent mutation in which codon is changed but amino acid is not change due to degeneracy. e.g.: `U UA rarr U UG`.

Discussion

681.	Gene regulation governing lactose operon of E.coli that involves the lac-I gene products isA. Negatively and repressible because repressor protein prevents transcriptionB. Feedback inhibition becausee excess of `beta`-galactosidase can switch off transcriptionC. Positive and inducible because it can be induced by lactoseD. Negative and inducible because repressor protein prevents transcription
Answer» Correct Answer - D Gene regulation governing lactose operon of E.coil that involves the lac I gene products is negative and inducible because repressor protein prevents transcription.

Discussion

682.	Gene regulation governing lactose operon of E. coli that involves the lac I gene product isA. Negative and inducible because repressor protein prevents transcriptionB. Negative and repressible because repressor protsin prevents trenscriptionC. Feedback inhibition decause excess of ~beta`- galactosidase can switch off transcripyionD. Positive and inducible because it can be induced by lactose
Answer» Correct Answer - a

Discussion

683.	Repeitive DNA are separated fom bulk geneomic DNA as different peak during density gradient centrifugation. The bulk DNA forms a major peaks and the other small peaks are refferred to asA. Repetitive DNAB. SNPs (Snips)C. Taq-DNAD. Satellite DNA
Answer» Correct Answer - D Repetitive DNA are separated from bulk genomic DNA as different peak during density gradient centrifugation. The bulk DNA forms a major peaks and the other small peaks are referred to as satellite DNA.

Discussion

684.	Inducible operon system usually accurs in (i) ___ pathways. Nutrient moleculses serve as (ii) ______ to stimulate production of the enzymes necessary for their breakdown. Genes for inducible operon are usually switched (iii)_____ and the repressor is synthesised in an (iv)____ form.A. `{:("(i)","(ii)","(iii)","(iv)"),("anabolic","corepressor","on","inactive"):}`B. `{:("(i)","(ii)","(iii)","(iv)"),("anabolic","inducer","off","active"):}`C. `{:("(i)","(ii)","(iii)","(iv)"),("catabolic","inducer","off","active"):}`D. `{:("(i)","(ii)","(iii)","(iv)"),("catabolic","corepressor","on","inactive"):}`
Answer» Correct Answer - c

Discussion

685.	When DNA is transferred from a culture of capsulated pneumococcus to a culture of non capsulated pneumococcus converting the latter into the former type, the process is known as.A. translocationB. conjugationC. transformationD. transduction
Answer» Correct Answer - C

Discussion

686.	Assertion : Transforming substance was not a protein or RNA. Reason : Proteases and RNAases do not affect transfomation.A. If both assertion and reason are true and the reason is the correct explanation of the assertion.B. If both assertion and reason are true but reason is not the correct explanation of the assertion.C. If assertion is true but reason is false.D. If both assertion and reason are false.
Answer» Correct Answer - A `` Protein - digesting enzymes (proteases) and RNA -digesting enzymes (Rnases) did not affect transformation, so the transforming substance was not a protein or RNA. `` Digestion with Dnase did inhibit transformation, suggesting that the DNA caused the transformation.

Discussion

687.	Assertion : In transforming principle, when streptococus pneumoniae (Pneumococcus) bacteria are grown on a culture plate, some produce smooth shiny colonies (S) while other produce rough colonies (R). Reason : S strain bacteria have a mucous (polysaccharide) coat, while R strain does not.A. If both assertion and reason are true and the reason is the correct explanation of the assertion.B. If both assertion and reason are true but reason is not the correct explanation of the assertion.C. If assertion is true but reason is false.D. If both assertion and reason are false.
Answer» Correct Answer - A `` When Streptococcus pneumoniae (pneumococcus) bacteria are grown on a culture plate, some produce smooth shiny colonies (S) while others produce rough colonies (R). `` This is because the S strain bacteria have a mucous (polysaccharide) coat, while R strain does not.

Discussion

688.	Strand X in the figure shows a small partsof a nucleic acid molecule Which pair of the following strands are complementary to strand X A. 1 and 3B. 2 and 4C. 1 and 2D. 3 and 4
Answer» Correct Answer - b

Discussion

689.	Assertion : If each strand from a parental DNA acts as template for synthesis of a new strand, the two double stranded daughter DNA thus produced would be indentical to the parental DNA molecule. Reason : The length of DNA double helix in a typical mammalian cell is calculate simply by multiplying the total number of bp with distance two consecutive bp.A. If both assertion and reason are true and the reason is the correct explanation of the assertion.B. If both assertion and reason are true but reason is not the correct explanation of the assertion.C. If assertion is true but reason is false.D. If both assertion and reason are false.
Answer» Correct Answer - B `` If each strand from a parental DNA acts as template for synthesis of anew strand. The two double stranded daughter DNA thus produced would identical to the parental DNA molecule. `` The length of DNA double helix in a typical mammalian cell is calculated simple by multiplying the total number of lbp with distance between two consecutive bp.

Discussion

690.	Assertion : If the sequence of bases in one strand is known then the sequence in other strand can be predicted. Reason : Both the strands of DNA are complementary of each other.A. If both assertion and reason are true and the reason is the correct explanation of the assertion.B. If both assertion and reason are true but reason is not the correct explanation of the assertion.C. If assertion is true but reason is false.D. If both assertion and reason are false.
Answer» Correct Answer - A The base pairing confers a very unique property to the polynucleotide chains. They are said to be completmentary to each other, and therefore if the sequence of bases in one strand is known then the sequence in other strand can be predicted.

Discussion

691.	Refer to the given steps of DNA strands (i) Exposure of DNA strands (ii) Synthesis of RNA primer (iii) Activation of deoxyribonucleotides (iv) Chain formatiion (v) Base pairing (vi) Proof reading and DNA repair ltviigt DNA polynerase attaches at Ori site Select the correct sequence of DNA replication.A. `(vii)to(iii)to(i)to(ii)to(v)to(iv)to(vi)`B. `(iii)to(i)to(vii)to(ii)to(v)to(iv)to(vi)`C. `(vii)to(i)to(iii)to(ii)to(v)to(iv)to(vi)`D. `(i)to(iii)to(ii)to(vii)to(v)to(iv)to(vi)`
Answer» Correct Answer - a (a)

Discussion

692.	Taylor conducted the experiment to prove semiconservative mode of chromosomereplication on`:`A. Vinca roseaB. Vicia fabaC. Drosophila melanogasterD. E. coli
Answer» Correct Answer - B

Discussion

693.	The unequivocal proof that DNA is the genetic material came from the experiments of -A. Hershey and ChaseB. Avery, MacLeod and McCartyC. Hargobind KhoranaD. Griffith
Answer» Correct Answer - A

Discussion

694.	In E.coli, lac operon is induced byA. promoter geneB. operator geneC. regulator geneD. allolactose
Answer» Correct Answer - D

Discussion

695.	In Escherichia coli, the product of `i` gene combines withA. operator gene to switch off structural genesB. inducer gene to switch off structural genesC. operator gene to swtich on structural genesD. regulator gene to swtich off structural genes
Answer» Correct Answer - A

Discussion

696.	In E. coli, an operator gene combines withA. inducer gene to switch on structural gene actionB. inducer genet o switch off structural gene actionC. regulator protein (repressor) to switch off structural gene actionD. regulator protein to switch on gene action
Answer» Correct Answer - C

Discussion

697.	Aporepressor is inactive repressor in Tryptophan repressible operon system. It isA. always proteinB. may be protein or a necleic acidC. a metaboliteD. a substrate
Answer» Correct Answer - A

Discussion

698.	Which one is nucleotide?A. Adenylic acid and guanosine monophosphateB. cytidylic acid and uridineC. uridylic acid and cytosineD. all of the above
Answer» Correct Answer - A

Discussion

699.	The pyrimidine base which confers additional stability to DNA over RNA is `:`A. AdenineB. CytosineC. GuanineD. Thymine
Answer» Correct Answer - D Pyrimidine base that has conferred additional stability to DNA over RNA ir thymine.

Discussion

700.	Histone occupies the major grooves of DNA at an angle ofA. `15^(@)`B. `90^(@)`C. `45^(@)` to the helix axisD. `30^(@)` to the helix axis
Answer» Correct Answer - c

Discussion

Explore topic-wise InterviewSolutions in .

The human chromoses scientists had no contribution in the development of the double helix model for the structure of DNAA. Chromosome 21 and YB. Chromosome 1 and XC. Chromosome 1 and YD. Chromosome X and Y

One strand of DNA (non template) has base sequence CAG, TCG, GAT. What will be the sequence of bases in m-RNAA. AGC,CTA, CTAB. GTA,AGC,CTCC. CAG,UCG,GAUD. GAC,TAG, CTA

The double helix model pf Watson and Crick is known asA. C- DNAB. B-DNAC. Z-DNAD. D- DNA

DNA template sequence of CTGATAGC is transcribed over mRNA asA. GUCTUTCGB. GACUAUCGC. GAUTATUGD. UACTATCU

Which of the following codon has no tRNAA. UAAB. UAUC. UGUD. UGC

Which property of DNA double helix led Watson and Crick to hypothesise semiconservative mode of DNA replication? Explain.

Which one is not transcribed by DNA ?A. ExonsB. IntronsC. DNAD. tRNA

Study the following tRNA molecule related with anti codon pairing with respective condons. Which types of tRNA is impossible A. T 1 and T2B. T1, T2 and T3C. T1 and T4D. T3, T4 and T5

Watson and Crick are known for their discovvery that DNAA. Is a single stranded helixB. Contains deoxyribose onlyC. Is a double stranded helixD. Synthesizes rRNA

In eukaryotic cell transcription, RNA splicing and RNA capping take place inside the OR Messenger RNA is produced inA. NucleusB. RibosomesC. E.RD. Dictyosomes

It ha s not escaped our notice t hat the specific pairing we have postulated immediately suggests a possible copying mechanism for genetic material. This is written byA. Meselson and StahlB. rchibold GarrodC. Secero OchoaD. Watson and Crick

The process of copying genetic information from one strand of DNA to RNA is termed as ________ .A. replicationB. transcriptionC. translationD. reverse transcription

RNA can acts as a. Genetic material b. Messenger c. Adapter molecule d. Structural molecule e. Catalytic moleculeA. b, c and eB. a, d and eC. a, b and cD. a, b, c, d and e

RNA is the genetic material inA. prokaryotesB. eukaryotesC. Tobacco Mosaic Virus (TMV)D. E.coli.

Which of the following statement are incorrect ? (i)RNA act as a genetic material as well as a catalyst. (ii)RNA is more stable than DNA (iii)RNA has evolved from DNAA. (i) and (iii) onlyB. (ii) and (iii) onlyC. (i), (ii) and (iii)D. (i) and (ii) only

RNA acts as genetic material inA. TMVB. OQ bacteriophageC. HIVD. All of the above

Which is incorrect about Hershey and Chase experiment ?A. Viruses grown in the presence of radioactive phosphorus contained radioactive protein but not radioactive DNAB. Viruses grown on radioactive sulfur contained radioactive DNA but not radioactive proteinC. Both A and BD. None of the above

(a) Mention two events in which DNA is unzipped. (b) Predict the consequences when both the template and the coding strands of a DNA segement participate in transcription process ?

Explain Hershey-Chase experiment. What was proved through this experiment ?

Jacob and Monod won Nobel Prize for their work onA. Operon modelB. Structure of geneC. Genetic diseasesD. Function of gene

Ribosomal RNA is synthesised inA. lysosmesB. nucleolusC. nucleoplasmD. ribosomes

Who synthesised the first artificial gene ?A. MorgenB. NirenbergC. KhoranaD. Mendel

A mutation at one base of the first codon of a gene produces a non-functional protein. Such a mutation is referred asA. Nonsense mutationB. Reverse mutationC. Frame shift mutationD. Mis-sence mutation

Repeitive DNA are separated fom bulk geneomic DNA as different peak during density gradient centrifugation. The bulk DNA forms a major peaks and the other small peaks are refferred to asA. Repetitive DNAB. SNPs (Snips)C. Taq-DNAD. Satellite DNA

When DNA is transferred from a culture of capsulated pneumococcus to a culture of non capsulated pneumococcus converting the latter into the former type, the process is known as.A. translocationB. conjugationC. transformationD. transduction

Strand X in the figure shows a small partsof a nucleic acid molecule Which pair of the following strands are complementary to strand X A. 1 and 3B. 2 and 4C. 1 and 2D. 3 and 4

Taylor conducted the experiment to prove semiconservative mode of chromosomereplication on`:`A. Vinca roseaB. Vicia fabaC. Drosophila melanogasterD. E. coli

The unequivocal proof that DNA is the genetic material came from the experiments of -A. Hershey and ChaseB. Avery, MacLeod and McCartyC. Hargobind KhoranaD. Griffith

In E.coli, lac operon is induced byA. promoter geneB. operator geneC. regulator geneD. allolactose

In Escherichia coli, the product of `i` gene combines withA. operator gene to switch off structural genesB. inducer gene to switch off structural genesC. operator gene to swtich on structural genesD. regulator gene to swtich off structural genes

In E. coli, an operator gene combines withA. inducer gene to switch on structural gene actionB. inducer genet o switch off structural gene actionC. regulator protein (repressor) to switch off structural gene actionD. regulator protein to switch on gene action

Aporepressor is inactive repressor in Tryptophan repressible operon system. It isA. always proteinB. may be protein or a necleic acidC. a metaboliteD. a substrate

Which one is nucleotide?A. Adenylic acid and guanosine monophosphateB. cytidylic acid and uridineC. uridylic acid and cytosineD. all of the above

The pyrimidine base which confers additional stability to DNA over RNA is `:`A. AdenineB. CytosineC. GuanineD. Thymine

Histone occupies the major grooves of DNA at an angle ofA. `15^(@)`B. `90^(@)`C. `45^(@)` to the helix axisD. `30^(@)` to the helix axis