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This section includes InterviewSolutions, each offering curated multiple-choice questions to sharpen your knowledge and support exam preparation. Choose a topic below to get started.
| 551. |
Which of the following steps in transcription is catalysed by RNA polymerase?A. InitationB. ElongationC. TerminationiD. All of the above |
| Answer» Correct Answer - b | |
| 552. |
Regulatory proteins are the accessory pro- teins that interact with RNA polymerase and affect its role in transcription. Which of the following statements is correct about regulatory protein?A. They only increase expressionB. They only decrease expressionC. They interact with RNA polymerase but do not affect the expressionD. They can act both as activators and as repressors |
| Answer» Correct Answer - d | |
| 553. |
Which of the following steps in transcription is catalysed by RNA polymerase?A. InitiationB. ElongationC. TerminationD. All of the above |
| Answer» Correct Answer - B | |
| 554. |
Control of gene experssion takes place at the level ofA. DNA-replicationB. TranscriptionC. TranslationD. None of the above |
| Answer» Correct Answer - B | |
| 555. |
During transcription, if the nucleotide sequence of the DNA strand that is being coded is ATACG, then the nucleotide sequence in the m RNA would beA. UAUGCB. UATGCC. TATGCD. TCTGG |
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Answer» Correct Answer - a a) Bases sequences in DNA will decide the base sequences in RNA. Uracil (U) will work as substitute for thymine (T) in mRNA. Complementary base printing for mRNA will be `{:(A,T,A,C,G),(U,A,U,G,C):}` |
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| 556. |
Statement A.The four nucleotide bases are not necessarily present in DNA in exact equal proportions B.The total amount of purines are equal to the total amount of pyrimidines C.DNA ligase enzyme act to hydrolyse or breakdown a polynucleotide chain into its component nucleotides D. Nuclease enzymes are capable of restoring an intact DNA duplex of the above statementsA. B is correct but A, C and D are wrongB. A and B are wrong but C and D are correctC. A and B are C are correct but D is wrongD. B,C and D are correct but A is wrong |
| Answer» Correct Answer - d | |
| 557. |
Number of nucleotide bases of a spiral of ds-DNA molecule isA. 5B. 10C. 20D. 40 |
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Answer» Correct Answer - C Number of nucleotide bases of a spiral of ds-DNA molecule is twenty (10 base pairs). |
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| 558. |
Assertion : Almost all (99.9%) nuceotide bases are exactly the same in all people. Reason : The human genome consists 3164.7 billion nucleotide bases.A. If both assertion and reason are true and the reason is the correct explanation of the assertion.B. If both assertion and reason are true but reason is not the correct explanation of the assertion.C. If assertion is true but reason is false.D. If both assertion and reason are false. |
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Answer» Correct Answer - C `**` Almost all (99.9%) nucleotide bases are exactly the same in all people. `**` The human genome consists 3164.7 million nucleotide bases. |
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| 559. |
During transcription, if the nucleotide sequence of the DNA strand that is being coded is ATACG, then the nucleotide sequence in the m RNA would beA. TATGCB. TCTGGC. UAUGCD. UATGG |
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Answer» Correct Answer - C If DNA has ATACG nucleotide sequence then the mRNA would contain UAUGC sequence . The formation of mRNA from DNA is termed as transcription. This process takes place in the nucleus (eukaryotes) or in the cytoplasm (prokaryotes). The base sequence of mRNA is complementary copy of the template DNA strand. |
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| 560. |
What is the type of coiling in DNAA. Right handedB. Left handedC. ZigzagD. Opposite |
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Answer» Correct Answer - A Type of coiling in DNA is right handed. |
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| 561. |
Nucleotide constituents/nitrogen bases of RNA areA. AGCUB. TCGUC. AGCTD. CTAU |
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Answer» Correct Answer - A Nucleotide constituents/nitrogen bases of RNA are AGCU. |
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| 562. |
Process used by Meselson and Stahl for studying semiconservative replication of DNA wasA. ChromatographyB. Density gradient centrifugationC. Buoyant density centrifugationD. Southern blotting |
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Answer» Correct Answer - B Process used by Meselson and Stahl for studying semiconservative replication of DNA was CsCl density gradient centrifugation. |
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| 563. |
There are 125 amino acids. We want to synthesize and mRNA. How many nitrogen bases are required to form sufficient condons to code all 125 amino acids?A. 375B. 125C. 42D. 3 |
| Answer» Correct Answer - A | |
| 564. |
Match the following `{:("A.","tRNA","1. Linking of aminoacids"),("B.","mRNA","2. Transfer of genetic information "),("C.","rRNA","3. Nucleolar organizing region "),("D.",Peptidyl transferase","4. ," Transfer of amino acid from cytoplasm of ribosome"):}`A. A tRNA 1. Linking of amino acidsB. (B ) mRNA 2. Transfer of genetic informationC. (C ) rRNA 3. Nucleolar organising regionD. (D ) Pertidyl transferase 4. Transfer of amino acid form cytoplasm of ribosome |
| Answer» Correct Answer - a | |
| 565. |
If in a test tube, mRNA of bacillus, tRNAs from the pancreas of rats and rRNA from salmonella are taken and sufficient number of amino acids are put, then the polypeptide synthesized will be of the nature ofA. BacillusB. rat body cellsC. both bacillus and rat body cellsD. salmonella |
| Answer» Correct Answer - A | |
| 566. |
In some viruses, DNA is synthesised by using RNA as template, Such a DNA is calledA. A-DNAB. B-DNAC. CdnaD. rDNA |
| Answer» Correct Answer - c | |
| 567. |
The RNA polymerase holoenzyme transcribesA. the promoter, structural gene and the terminator regionB. the promoter and the terminator regionC. the structural gene and the terminator regionD. the structural gene only. |
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Answer» Correct Answer - d |
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| 568. |
Which one of the following also acts as a catalyst in a becterial cell Or Which one of the following rRNA acts as stuctural RNA as well as ribozyme in bacterialA. 23 sr RNAB. 5 sr RNAC. sn RNAD. hnRNA |
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Answer» Correct Answer - a a) 23 S rRNA is catalytic RNA |
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| 569. |
In a hair pin modle of RNA which nitrogen base is present at the short endA. AdenineB. GuanineC. ThymineD. Cytossine |
| Answer» Correct Answer - b | |
| 570. |
The fact that purine base always paired through hydrogen bonds with a pyrimidine base leads to, in the DNA double helix:A. the antiparallel natureB. the semiconservative natureC. uniform width throughout DNAD. uniform length in all DNA |
| Answer» Correct Answer - c | |
| 571. |
In a 3.2 Kbp long piece of DNA , 820 adenine bases were found. What would be number of cyosine basesA. 780B. 1560C. 740D. 1480 |
| Answer» Correct Answer - a | |
| 572. |
In the double helix modle of DNA , how far is each base pair from the next base pairA. 3.4 nmB. 0.34 nmC. 2.0 nmD. 34 nm |
| Answer» Correct Answer - b | |
| 573. |
In the double helix modle of DNA , how far is each base pair from the next base pairA. 3.4 nmB. 0.34 nmC. 20 nmD. 34 nm |
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Answer» Correct Answer - B The two chains are coiled in a right-handed fashion. The pitch of the helix is 3.4 nm (a nanometre is one billionth of a metre, that is `10^(-9)` m) and there are roughly 10 bp in each turn. Consequently, the distance between a bp in a helix is approximately equal to 0.34 nm. |
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| 574. |
In DNA of certain organisms, guanine constitutes 20% of the bases. What percentage of the bases would be adenine |
| Answer» Correct Answer - d | |
| 575. |
In sea urchin DNA, which is double stranded, 17% of the bases were show to be cytosine. The percentages of the other three bases expected to be present in this DNA areA. G 17%, A 16 .5%, T 32.5 %B. G 17 %, A 33%, T 33%C. G 8.5%, A 50%, T 24.5 %D. G 34 %, A 24.5% , T24.5% |
| Answer» Correct Answer - b | |
| 576. |
In sea urchin DNA, which is double stranded, 17% of the bases were show to be cytosine. The percentages of the other three bases expected to be present in this DNA areA. G17%,A 16.%, T 32.5%B. G 17%, A33, T33%C. G 8.5%, A 50%, T 24.5%D. G 34%, A 24.5%, T 24.5% |
| Answer» Correct Answer - B | |
| 577. |
DNA fragments areA. positively chargedB. negatively chargedC. neutralD. either positively or negatively charged depending on their size |
| Answer» Correct Answer - B | |
| 578. |
Which of the following step of translation does not consume a high energy phosphate bondA. TranslocationB. Amino acid activationC. Peptidyl transferase reactionD. Aminoacyl `t RNA` binding to A-site |
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Answer» Correct Answer - a a) Translocation means the shifting of ribosomes along m-RNA. This step requires elongation factor (Translocase) and simultaneously the hydrolysis of GTP takes place that provides energy for the translocation (not ATP). |
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| 579. |
Which step of translation does not consume high energy `PO_(4)` bond?A. TranslocationB. tRNA activationC. Amino acid activationD. Peptydyl transferase reaction |
| Answer» Correct Answer - D | |
| 580. |
The process of translation is `:`A. ribosome synthesisB. protein synthesisC. DNA synthesisD. RNA synthesis |
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Answer» Correct Answer - B Translation is the process of protein synthesis in which the triplet base seuences of mRNA molecules is converted into a specific sequences of amino acids in a polypeptide chain , this occurs on ribosomes. |
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| 581. |
A DNA with unequal nitrogen bases would most probably beA. single strandedB. double strandedC. triple strandedD. four stranded |
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Answer» Correct Answer - A A single stranded DNA do not possess its cmplementary base pairs so it would have unequal nitrogen bases. |
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| 582. |
The number of base substitution possible in amino acid codons isA. 261B. 264C. 535D. 549 |
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Answer» Correct Answer - D There are 64 codons out of which 61 codes for amino acid . Each codon possess 3 bases which can undergo transition and transversion , so the number of base substitution possible in amino acid codon is `61xx3^(2)=549`. |
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| 583. |
Nucleosome core is made of :A. H1 , H2A , H2B and H3B. H1 , H2A , H2B and H4C.D. H1 , H2A, H2B, H3 and H4 |
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Answer» Correct Answer - D A nucleosome is an octamer of histone proteins and has a core of 8 molecules of histone proteins (two each of H2A, H2B, H3 and H4] wrapped by two turns of DNA. |
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| 584. |
Assertion : In transcription only a segment of DNA and only one of the strands is copied into RNA. Reason : The process of replication, once set in, duplicates the total DNA os an organism.A. If both assertion and reason are true and the reason is the correct explanation of the assertion.B. If both assertion and reason are true but reason is not the correct explanation of the assertion.C. If assertion is true but reason is false.D. If both assertion and reason are false. |
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Answer» Correct Answer - B `**` In transcription only a segment of DNA and only one of the strands is copied into RNA. `**` The process of replication, once set in, duplicates the total DNA of an organism. |
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| 585. |
Read statements `a-d`. (a) In transcription, adenosine pairs with uracil (b) Regulation of lac operon by repressor is positive regulation (c) Human genome has approximate 50,000 genes (d) Haemophilia is sex-linked recessive disease How many of above statement are correct ?A. 2B. 3C. 4D. 1 |
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Answer» Correct Answer - A `**" "`a and d are correct. `**" "`Regulation lac operon by repressor is positive regulation. `**" "`Human genome has approximate 30,000 genes. |
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| 586. |
Read statements `a-d`. (a) In transcription, adenosine pairs with uracil (b) Regulation of lac operon by repressor is positive regulation (c) Human genome has approximate 50,000 genes (d) Haemophilia is sex-linked recessive disease How many of above statement are correct ?A. FourB. OneC. TwoD. Three |
| Answer» Correct Answer - C | |
| 587. |
Read the following four statements (A-D) ltbr gt In transcription, adenosine pair uracil Regulation of lac operon by repressor is refferred to as positive regulation The human genome has approximately 50,000 genes ltbr gt Haemophilia is sex - linked recessive disease How many of the above statements are rightA. TwoB. ThreeC. FourD. One |
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Answer» Correct Answer - a a) Regulatioin of Iac operon by repressor is referred as negative regulation. Human genome has approximately 30000 genes. |
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| 588. |
With regard to mature mRNA in eukaryotesA. Exons and introns do not appear in the mature RNAB. exons appear but introns do not appear in the mature RNAC. Introns appear but exons do not appear in the mature RNAD. Both exons and introns appear in the mature RNA |
| Answer» Correct Answer - b | |
| 589. |
A solution of purified DNA will have pHA. BasicB. Highly basicC. AcidicD. Neutral |
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Answer» Correct Answer - C A solution of purified DNA will have acidic. pH |
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| 590. |
Which of the following amino acids has single codon?A. IsoleucineB. TryptophanC. valine-methionine-glycine-histidine-lysineD. Arginine |
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Answer» Correct Answer - B Only methionine and tryptophan are coded by single codons. |
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| 591. |
Which amino acid has a single codon ?A. SerineB. CysteineC. TyrosineD. Tryptophan |
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Answer» Correct Answer - D Tryptophan amino acid has a single codon (UGG). |
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| 592. |
Assertion : E. coli divides in 20 minutes. Reason : In E. coli the process of replication completes within 18 minutes.A. If both assertion and reason are true and the reason is the correct explanation of the assertion.B. If both assertion and reason are true but reason is not the correct explanation of the assertion.C. If assertion is true but reason is false.D. If both assertion and reason are false. |
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Answer» Correct Answer - B `**` E. coli divides in 20 minutes. `**` In E. coli the process of replications completes within 18 minutes. |
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| 593. |
The given diagram illustrates A. Chromosome walkingB. Homoral AnalysisC. Human Genome ProjectD. Method of DNA fingerprinting |
| Answer» Correct Answer - c | |
| 594. |
The adjacent figure represents the structure of basic 30 min fibre of chormosome of eukaryotes . Choose the correct option in which F1, F2 A and B are correctly identified |
| Answer» Correct Answer - d | |
| 595. |
Whihc of the following pair of amino acids are acidicA. Glycine and glutamateB. Aspartate and valineC. Alanin and methionineD. Glutamate and aspartate |
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Answer» Correct Answer - d d) Glutamate [Glutamic acid] and Aspartae [Aspartic acid] contain more -COOH groups and are considered acidic amino acids. |
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| 596. |
Study the following whihc shows the synthesis of part of a protein molecule The DNA strand by which `Mrna_(2)` was synthesised isA. CUUGACCUGGGAB. GAACUGGACCCUC. CTTGACCTGGGAD. GAACTGGACCCT |
| Answer» Correct Answer - c | |
| 597. |
Uridine, present only in RNA isA. NucleosideB. NucleotideC. PurineD. Pyrimidine |
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Answer» Correct Answer - d d) Uracil base is found in RNA, in this way, uridine monophosphate is the nucleotide of RNA. |
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| 598. |
The figure shows a hypthetical tetrapeptide portion of a protein with parts labelled A-D. Which one of the following option is correct A. D is the acidic amion acid - glutamic acidB. C is an aromatic amino acid - trytophanC. A is the C- terminal amino acid and D is N terminal amino acidD. A is the sulphur containing amino acid - methionie |
| Answer» Correct Answer - a | |
| 599. |
Aminoacylation of tRNA is essential forA. Replication of RNAB. Formation of peptide bondC. SplicingD. Initiation of transcription |
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Answer» Correct Answer - B `**" "`The amino acids are joined by a bond which is known as a peptide bond. `**" "`Formation of a peptide bond reuires energy. Therefore, in the phase itself amino acids are activated in the presence of ATP and linked to their cognate tRNA-a process commonly called as activation of charging of tRNA or aminoacylation of tRNA to be more specific. `**" "`Amino acid `+ATP rarr` Aminoacyl `AMP+P Pi` |
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| 600. |
Which of the character is not applicable to t-RNAA. It is the smallest of the RNAsB. It acts as an adapter for amino acidsC. It has a clover leaf like structureD. It is the largest of the RNAs |
| Answer» Correct Answer - d | |