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This section includes InterviewSolutions, each offering curated multiple-choice questions to sharpen your knowledge and support exam preparation. Choose a topic below to get started.
| 601. |
Go through the following statements: (i) Viruses are obligate parasites (ii) Viruses that infect plants in general have single stranded DNA (iii) Bacteriophages are double stranded DNA viruses. (iv) The coat is made of protein subunits called nucleomeres. Find the correct statementsA. (i), (ii), (iv)B. (i),(iii),(iv)C. (i),(iii)D. (i),(iv) |
| Answer» Correct Answer - C | |
| 602. |
Bacterial transduction is phage mediated genetic transfer and was discovered in salmonella byA. zinder and LederbergB. Tatum and LederbergC. Beadle and TatumD. Avery, Macleod and Mccarty |
| Answer» Correct Answer - A | |
| 603. |
The single stranded DNA of phage `phixx174` has 5400 nucleotides. If average protein contains 200 amino acids, how many different proteins could this phage DNA code?A. 100B. 90C. 9D. 27 |
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Answer» Correct Answer - C 5400 nucleotides in DNA will form 5400`-:`3=1800 codons. 200 aminoacids, i.e., 200 codons form one protein and therefore, `1800-:`200=9 proteins can be formed. |
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| 604. |
DNA repairing is done byA. LigasesB. DNA Polymerase IIIC. DNA polymerase IID. DNA polymerase I |
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Answer» Correct Answer - d d) DNA polymerase I is a reparing enzyme which introduce and join the defected segment of DNA. |
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| 605. |
The enzyme required to catayze the polymerzatio of deoxynucleotides isA. DNA ligaseB. DNA polymeraseC. beta-galactosidaseD. Transacetyase |
| Answer» Correct Answer - b | |
| 606. |
If there are 120 adenine molecule in abDNA double helical structure showing 20 coils, what is the number of pyrimidine nucleotides forming three hydrogen bonds in itA. 80B. 100C. 120D. 140 |
| Answer» Correct Answer - a | |
| 607. |
Who proved that DNA is the basic genetic material ?A. Griffith/Avery et alB. WatsonC. Boveri and SuttonD. Hershey and Chase |
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Answer» Correct Answer - D Hershey and Chase proved that DNA is basic genetic material. |
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| 608. |
Who proved that DNA is the basic genetic material ?A. GriffithB. WastonC. Boveri and SuttonD. Hershey and Chase |
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Answer» Correct Answer - D Hershey and Chase [1952] proved that DNA is basic genetic material. |
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| 609. |
Who proved experimentally that DNA is genetic material ?A. O. Avery and ColleaguesB. J. Waston and F. CrickC. W. Arber and ColleaguesD. G. Mendel |
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Answer» Correct Answer - A O. Avery and Colleagues proved experimentally that DNA is genetic material. |
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| 610. |
In DNA finger printing, DNA bridization with the help of specific DNA probe is done throughA. Western blottingB. Northern blottingC. Southern blottingD. Eastern blotting |
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Answer» Correct Answer - C In DNA of specific DNA probe is done through Southern blotting. |
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| 611. |
If one strand of DNA has the nitrogenous base sequence as ATCTG, what would be the complementary RNA strand sequence ?A. UAGACB. AACTGC. ATCGUD. TTAGU |
| Answer» Correct Answer - A | |
| 612. |
Which of the following nitrogenous base is double ringed ?A. GuanineB. ThymineC. UracilD. Cytosine |
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Answer» Correct Answer - A Guanine and adenine (purine) nitrogenous base are double ringed. |
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| 613. |
Which of the following biomolecules does have phosphodiester bondA. Nucleic acids in a nucleotideB. Fatty acids in a diglycerideC. Monosaccharides in a polysaccharideD. Amino acids in a polypeptide |
| Answer» Correct Answer - A | |
| 614. |
Identify the correct order of organisation of genetic material from largest to smallest.A. Genome, chromosome, nucleotide, geneB. Genome, chromosome, gene, nucleotideC. Chromosome, genome, nucleotide, geneD. Chromosone, gene, genome, nucleotide |
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Answer» Correct Answer - B The correct order of organisation of genetic material from largest to smallest : Genome, chromosome, gene and nucleotide. |
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| 615. |
Identify the correct order of organisation of genetic material from largest to smallest :A. Chromosome , gene , genome , nucleotideB. Genome , chromosome , nucleotide geneC. Genome , chromosome , gene , nucleotideD. Chromosome , genome , nucleotide , gene |
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Answer» Correct Answer - C The correct order of organisation of genetic material from largest to smallest is as follows Genome , chromosome , gene , nucleotide. Genome It is the total genetic material of a individual . Chromosome It is a packed and organised structure containing most of the DNA of a living organism. Gene It is a segment of DNA that encodes for a protein. Nucleotide It is one of the structural components, or building blocks , of DNA and RNA. |
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| 616. |
Identify the correct order of organisation of genetic material from largest to smallest :A. Chromosome, genome, nucleotide, geneB. Chromosome, gene, genome, nucleotideC. Genome, chromosomes, nucleotide, geneD. Genome, chromosome, gene, nucleotide |
| Answer» Correct Answer - D | |
| 617. |
Which of the following is required as inducer(s) for the expression of Lac operon ?A. GalactoseB. Lactose permese and transacetylaseC. Lactose and galactsoeD. Glucose |
| Answer» Correct Answer - B | |
| 618. |
DNA finger printing technique was first developed byA. Jeffreys, Wilson and ThienB. Boysen and JensenC. Sleiden and SchwannD. Edward and Steptoe |
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Answer» Correct Answer - a a) The technique of DNA fingerprinting was initially developed by Alec Jeffreys. He used a satellite DNA as probe that shows very high degree of polymorphism. It was killed variable number of tanderm repeats. |
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| 619. |
cDNA probes are copied from the messenger RNA molecules with the help ofA. Restriction enzymesB. Reverse transcriptaseC. DNA polymeraseD. Adenosine diaminase |
| Answer» Correct Answer - b | |
| 620. |
If the total amount of adenine and thymine in a double stranded DNA is 45% the amount of guanine this DNA will be `:`A. `22.5%`B. `27.5%`C. `45%`D. `55%` |
| Answer» Correct Answer - B | |
| 621. |
If the total amount of adenine and thymine in a double- stranded DNA is 45%, the amount of guanine in this DNA will beA. 22.5B. 27.5C. 45D. 55 |
| Answer» Correct Answer - b | |
| 622. |
What is the first step in the Southern Blot techniqueA. Denaturation of DNA on the gel for hybridization with specific prodeB. Production of a group of genetically identical cellsC. Digestion of DNA by restriction enzymeD. Denaturation of DNA from a nucleated cell such as the one from the scene of crime. |
| Answer» Correct Answer - C | |
| 623. |
Asseration : DNA found in mitochondria and chloroplast are called prochromosome. Reason : They are similar to prokaryotic chromosome.A. If both the assertion and the reason are true and the reason is a correct explanation of the assertion.B. If both the assertion and reason are true but the reason is not a correct explanation of the assetionC. If the assertion is true but the reason is falseD. If the both the assertion and reason are false |
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Answer» Correct Answer - a Prokaryotic chromosome (prochromosome )consists of a naked double strand of DNA that is the DNA is not v |
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| 624. |
Which of the following statements is not true for cancer cells is relation to mutations ?A. Mutations inactivata the cell controlB. Mutations inhibit production of telomeraseC. Mutations in proto-oncogenes accelerate the cell cycleD. Mutations destroy telomerase inhibitors |
| Answer» Correct Answer - B | |
| 625. |
Differentiation of organs and tissues in a develping organism, is assoiated withA. Developmental mutationsB. Differential expression of genesC. Lethal mutationsD. Deletion of genes |
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Answer» Correct Answer - b b) Differential expression of genes is responsible of different type of protein by which different cells of organs are formed. |
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| 626. |
GAATTC is the recognization site for which of the following restriction endonucleaseA. Hind IIIB. EcoR IC. Bam ID. Hae III |
| Answer» Correct Answer - b | |
| 627. |
Telemere repetitive DNA sequences control the function of eukarote chromosomes because theyA. act as repliconsB. are RNA transcription initiatorC. help chromosome pairingD. prevent chromosomes loss |
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Answer» Correct Answer - D Telomeres , i.e. the ends of chromosome , have repetitive DNA sequences and are stable and resistant to exonuclease digestion hence, prevent chromosome loss. |
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| 628. |
Molecular basis of organ differentiation depends on the modulation in transcription byA. RNA polymeraseB. ribosomeC. transcription factorD. anticodon |
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Answer» Correct Answer - C Transcription factor is molecular basis of organ differentiation. |
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| 629. |
The length of DNA molecile greatly exceeds the dimensions of the nucleus in eukaryotic cell. How is this DNA accommodatedA. Deletion of non -essential genesB. Super- coiling in nucleosomesC. DNA ase digestionD. Through elimination of repetitive DNA |
| Answer» Correct Answer - b | |
| 630. |
The length of DNA molecile greatly exceeds the dimensions of the nucleus in eukaryotic cell. How is this DNA accommodatedA. Deletion of non - essential geneB. Super - coiling in nucleosomesC. DNAse digestionD. Through elimination of repetitive DNA |
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Answer» Correct Answer - B In eqkaryotic cells , DNA is accommodated by super- coiling in nucloesomes. |
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| 631. |
In prokaryotes, first amino acid taking part in protein synthesis isA. metB. `f^(met)`C. valD. none of these |
| Answer» Correct Answer - B | |
| 632. |
Which cannot be used for DNA finger printing in humans ?A. LeucocytesB. Erythrocytes/RBCsC. Hair bulbsD. Sperms |
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Answer» Correct Answer - B Erythrocytes/RBCs are used for DNA finger printing in humans because they are without nucleus /DNA |
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| 633. |
The enzyme that breaks` H_(2)` bonds in DNA isA. HelicaseB. TopoisomeraseC. LigaseD. Polymerase |
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Answer» Correct Answer - a a) Enzymes helicase unwinds the DNA helix and unzips the two strands of DNA. |
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| 634. |
Which one of the following is most specific region of tRNA?A. amino acid attachment siteB. amino acid recognition siteC. codon recognition siteD. Ribosome recognition site. |
| Answer» Correct Answer - C | |
| 635. |
if a labelled DNA (with a heavy isotope) replicates in conservative manner in a normal medium then ini `F_(1)`A. both daughter DNA molecules will be heavyB. one DNA molecule will be heavy and one lightC. both DNA molecules will be hybridD. all are possible |
| Answer» Correct Answer - B | |
| 636. |
Human genome project was discoverd byA. Francis Collins and RoderickB. Watson and CrickC. Beadle and TatumD. Paul Berg and Wollman |
| Answer» Correct Answer - a | |
| 637. |
The main aim of the human genome project is..........A. To introduce new gene into humansB. To identify and sequence all the genes present in human DNAC. To identify better techiques for comparing two different human DNA samplesD. To remove disease causing genes from human DNA |
| Answer» Correct Answer - b | |
| 638. |
Go through the features of human genome (i) Largest human gene is dystrophin with 2.4 million bases (ii) Chromosome 1 has maximum number of genes, i.e., 2968 and y-chromosome has minimum number, i.e., 231 (iii) the human genome contains 3164.7 billion nucleotide bases (iv) The total number of genes is estimated at 30,000 Which of these are correct?A. (i), (ii) & (iii)B. (ii),(iv)C. (i), (ii) & (iv)D. All are correct |
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Answer» Correct Answer - C Human genome contains 3164.7 million nucleotide bases. |
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| 639. |
Regulation of gene expression in eukaryotes could be exerted at a. Transcriptional level (formation of primary transcript) b. Processing level (regulation of splicing) c. Transport of mRNA from nucleus to the cytoplasm d. Translational levelA. a, b and cB. b, c and dC. a, c and dD. a, b, c, and d |
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Answer» Correct Answer - D In eukaryotes, the regulation could be exerted at (i) Transcriptional level (formation of primary transcript), (ii) Processing level (regulation of splicing), (iii) Transport of mRNA from nucleus to the cytoplasm, (iv) Translation level. |
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| 640. |
Site for protein/peptide synthesis is |
| Answer» Correct Answer - Ribosomes. | |
| 641. |
Which of the following statements is worng for viroidsA. They are smaller than virusesB. they cause infectionsC. their RNA is of high molecular weightD. they lack a protein coat |
| Answer» Correct Answer - C | |
| 642. |
Double helical model of DNA molecule was proposed by `:`A. Beadle and TatumB. Schleiden and SchwannC. Watson and CrickD. Hooke and Huxley |
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Answer» Correct Answer - C Double helix DNA structure was proposed by Watson and Crick. |
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| 643. |
Who was awarded Nobel Prize for contribution of finding nature of gene ?A. De VriesB. T.H. MorganC. H.. MullerD. Darwin |
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Answer» Correct Answer - B T.H. Morgan was awarded Nobel Prize (1933) for contribution of finding nature of gene. |
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| 644. |
Spliceosomes are not found in cell ofA. plantsB. fungiC. animalsD. bacteria |
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Answer» Correct Answer - D Spliceosome is a large molecules complex found in nucleus of eukaryotic cells of plants , animals and fungi , etc. it is assembled from snRNAs and protein complexes that plays an important role in splicing of introns. Spliceosome is absent in cells of bacteria. |
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| 645. |
Khorana first deciphered the triplet codons ofA. serine and isoleucineB. threonine and histidineC. tyrosine and tryptophanD. phenylalanine and methionine |
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Answer» Correct Answer - B Dr Hargobind Khorana deciphered first triplet codon of threonine and histidine. |
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| 646. |
Anticodon is an unpaired triplet of bases in an exposed position ofA. mRNAB. rRNAC. tRNAD. sRNA |
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Answer» Correct Answer - C tRNA possess anticodon stem which includes five paired bases . The anticodon loop consists of 7 unpaired bases . The third , fourth and fifth of which form anticodon. This anticodon permits temporary complementary pairing with three bases on mRNA. |
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| 647. |
The number of triplet codons having all the three bases same in 64 triplet codons is `:`A. 3B. 6C. 4D. 2 |
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Answer» Correct Answer - C Number of triplet codons having all three bases same in 64 triplet codons having all there bases same in 64 triplet codons are four (i.e. UUU, AAA, GGG and CCC). |
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| 648. |
The technique used for analysis of RNA is calledA. Northern BlottingB. western blottingC. Southern blottingD. ELISA |
| Answer» Correct Answer - A | |
| 649. |
DNA synthesis can be specifically measured by estimating the incorporation of radio labelledA. UracilB. Ribose sugarC. ThymidineD. Adenine |
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Answer» Correct Answer - C DNA synthesis can be measured by estimating incorporation of radio-labelled Thymidine (by Taylor). |
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| 650. |
Who amongst the following scientists had no contribution in the development of the double helix model for the structure of DNAA. Rosalind FranklinB. Maurice WilkinsC. Erwin ChargaffD. Meselson and Stahl |
| Answer» Correct Answer - d | |