This section includes InterviewSolutions, each offering curated multiple-choice questions to sharpen your knowledge and support exam preparation. Choose a topic below to get started.
| 101. |
Which of the following chromatins are said to be transcriptionally active and inactive respectively?(a) Euchromatin, Heterochromatin(b) Euchromatin, Prochromatin(c) Prochromatin, Euchromatin(d) Heterochromatin, EuchromatinThis question was posed to me in an interview.My doubt stems from Packaging of DNA Helix in portion Molecular Basis of Inheritance of Biology – Class 12 |
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Answer» CORRECT choice is (a) Euchromatin, Heterochromatin The explanation is: Inside the TYPICAL structure of a nucleus, the part of the chromatin which is considerably loose and stains light is said to be the Euchromatins. Likewise, the part of the chromatin which is considerably DENSE and stains dark is said to be the Heterochromatins. The part which is loose is said to be transcriptionally active, and the dense part is said to be transcriptionally INACTIVE. |
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| 102. |
How many nucleosomes are present in a mammalian cell?(a) 20 million(b) 30 million(c) 40 million(d) 10 millionThis question was addressed to me in examination.My doubt stems from Packaging of DNA Helix in division Molecular Basis of Inheritance of Biology – Class 12 |
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Answer» Right choice is (b) 30 million |
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| 103. |
When the negatively charged DNA combines with the positively charged histone octamer, which of the following is formed?(a) Nucleus(b) Nucleoid(c) Nucleosome(d) NucleosomeThis question was addressed to me in an online interview.This intriguing question originated from Packaging of DNA Helix topic in division Molecular Basis of Inheritance of Biology – Class 12 |
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Answer» The CORRECT ANSWER is (c) Nucleosome |
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| 104. |
How many bp are present in a typical nucleosome?(a) 200 bp(b) 100 bp(c) 300 bp(d) 90 bpI got this question by my college director while I was bunking the class.Enquiry is from Packaging of DNA Helix in portion Molecular Basis of Inheritance of Biology – Class 12 |
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Answer» Right option is (a) 200 bp |
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| 105. |
What are the thread-like stained structures present in the nucleus known as?(a) Chromosome(b) Chromatid(c) Chromatin(d) ChloroplastI have been asked this question in a job interview.Enquiry is from Packaging of DNA Helix topic in chapter Molecular Basis of Inheritance of Biology – Class 12 |
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Answer» Right option is (c) Chromatin |
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| 106. |
What are the set of positively charged basic proteins called as?(a) Histidine(b) DNA(c) RNA(d) HistonesThis question was addressed to me in exam.I would like to ask this question from Packaging of DNA Helix topic in portion Molecular Basis of Inheritance of Biology – Class 12 |
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Answer» The correct choice is (d) Histones |
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| 107. |
The DNA of the E. coli is scattered throughout the cell.(a) True(b) FalseI had been asked this question during a job interview.This interesting question is from Packaging of DNA Helix in chapter Molecular Basis of Inheritance of Biology – Class 12 |
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Answer» The correct choice is (B) False |
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| 108. |
Which of the following is not a part of the nucleotide?(a) Phosphate group(b) Nitrogenous base(c) Pentose sugar(d) GuanosineThis question was addressed to me in a job interview.This interesting question is from Structure of a Polynucleotide Chain topic in portion Molecular Basis of Inheritance of Biology – Class 12 |
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Answer» Correct CHOICE is (d) Guanosine |
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| 109. |
What is the length of the DNA double helix, if the total number of bp (base pair) is 6.6 x 10^9?(a) 2.2 m/bp(b) 2.5 m/bp(c) 2.2 m(d) 2.5 mThis question was addressed to me in a job interview.The query is from Packaging of DNA Helix topic in division Molecular Basis of Inheritance of Biology – Class 12 |
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Answer» The correct answer is (c) 2.2 m |
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| 110. |
Which of the following occurs in the process of central dogma reverse?(a) Conversion of a strand of mRNA to DNA(b) Changes in the chromosomal karyotype(c) Gene replication process(d) Protein production processThis question was posed to me in final exam.My doubt is from Structure of a Polynucleotide Chain topic in portion Molecular Basis of Inheritance of Biology – Class 12 |
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Answer» The correct option is (a) Conversion of a strand of MRNA to DNA |
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| 111. |
Which of the following ensures the stability of the helical structure of a DNA?(a) Presence of repetitive structures of a DNA code(b) Stacking of one base pair over the other(c) Presence of aneuploidy(d) Occurrence of chromosomal rearrangementsI had been asked this question during an interview.The question is from Structure of a Polynucleotide Chain topic in division Molecular Basis of Inheritance of Biology – Class 12 |
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Answer» RIGHT option is (b) Stacking of one base pair over the other To explain I would say: When one base pair is STACKED over the other in a helical fashion, the DNA will be stable. A right-handed curving fashion is seen in the DNA. When repeating structures are present, the DNA will not be stable. Aneuploidy is in relevance to the abnormality in the number of chromosomes. When CHROMOSOMAL rearrangements occur, deletion, DUPLICATION, translocations and inversions may occur. There will not be any stability. |
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| 112. |
Which is the correct complementary strand for AGAATTCGC?(a) CTCCGGATA(b) GAGGCCTAT(c) TCTTAAGCG(d) GTGGCCATAI had been asked this question in an internship interview.This interesting question is from Structure of a Polynucleotide Chain in portion Molecular Basis of Inheritance of Biology – Class 12 |
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Answer» The correct answer is (C) TCTTAAGCG |
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| 113. |
Which of the following enzymes are used to transcript a portion of the DNA into mRNA?(a) RNA polymerase(b) DNA polymerase(c) Protein polymerase(d) HydrolaseI have been asked this question in an online quiz.This intriguing question originated from Structure of a Polynucleotide Chain in division Molecular Basis of Inheritance of Biology – Class 12 |
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Answer» The correct choice is (a) RNA polymerase |
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| 114. |
Which among the following is the exact ratio of guanine to cytosine in a DNA double helical structure?(a) 3:2(b) 2:1(c) 1:3(d) 1:1The question was asked by my college professor while I was bunking the class.Query is from Structure of a Polynucleotide Chain in division Molecular Basis of Inheritance of Biology – Class 12 |
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Answer» Correct choice is (d) 1:1 |
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| 115. |
Who considered DNA as a “Nuclein”?(a) James Watson(b) Friedrich Meischer(c) Francis Crick(d) Rosalind FranklinThe question was posed to me in a job interview.Question is taken from Structure of a Polynucleotide Chain in division Molecular Basis of Inheritance of Biology – Class 12 |
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Answer» The correct option is (b) Friedrich Meischer |
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| 116. |
What is chemical name for thymine known as?(a) 5-methoxy uracil(b) 3-methoxy uracil(c) 5-methyl uracil(d) 3-methy uracilThis question was addressed to me in my homework.I need to ask this question from Structure of a Polynucleotide Chain in portion Molecular Basis of Inheritance of Biology – Class 12 |
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Answer» Right option is (C) 5-methyl URACIL |
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| 117. |
Through which among the following linkages are the two nucleotides connected through the 3’-5’ end?(a) Phosphodiether linkage(b) Phosphodisulphide linkage(c) Phosphodinitrate linkage(d) Phosphodiester linkageI got this question in an online interview.This interesting question is from Structure of a Polynucleotide Chain topic in section Molecular Basis of Inheritance of Biology – Class 12 |
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Answer» The correct OPTION is (d) PHOSPHODIESTER linkage |
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| 118. |
Thymine is present in the place of Uracil in DNA.(a) True(b) FalseThe question was asked at a job interview.My enquiry is from Structure of a Polynucleotide Chain in chapter Molecular Basis of Inheritance of Biology – Class 12 |
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Answer» The correct OPTION is (a) True |
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| 119. |
By which of the following bonds, a nitrogenous base is linked to the pentose sugar?(a) Phosphate bond(b) Ester bond(c) Peptide bond(d) N-glycosidic bondThe question was asked in semester exam.The question is from Molecular Basis of Inheritance in division Molecular Basis of Inheritance of Biology – Class 12 |
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Answer» The correct choice is (d) N-glycosidic bond |
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| 120. |
By which of the following bonds, a nitrogenous base is linked to the pentose sugar?(a) Phosphate bond(b) Ester bond(c) Peptide bond(d) N-glycosidic bondThis question was addressed to me in exam.Question is taken from Molecular Basis of Inheritance in portion Molecular Basis of Inheritance of Biology – Class 12 |
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| 121. |
Which of the following statement is incorrect with respect to pyrimidines?(a) Heterocyclic(b) 7 membered ring(c) Cytosine is an example of pyrimidine(d) Single-ring structureThe question was posed to me in semester exam.Origin of the question is Molecular Basis of Inheritance topic in division Molecular Basis of Inheritance of Biology – Class 12 |
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Answer» Right option is (b) 7 membered ring |
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| 122. |
Which of the following statements is correct with respect to purines?(a) Purines are heterocyclic compounds(b) Purines are 7 membered structure(c) Purines are single-ring structure(d) Thymine is an example of purineThis question was posed to me in an interview.My enquiry is from Molecular Basis of Inheritance in division Molecular Basis of Inheritance of Biology – Class 12 |
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Answer» Correct choice is (a) Purines are heterocyclic COMPOUNDS |
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| 123. |
How many components are present in the basic unit of DNA?(a) One(b) Two(c) Three(d) FourI had been asked this question in quiz.My question is from Molecular Basis of Inheritance in division Molecular Basis of Inheritance of Biology – Class 12 |
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Answer» Correct answer is (c) Three |
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| 124. |
The genetic material of humans is double-stranded DNA which is circular in shape.(a) False(b) TrueThis question was posed to me by my college professor while I was bunking the class.Question is taken from Molecular Basis of Inheritance in division Molecular Basis of Inheritance of Biology – Class 12 |
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Answer» The correct answer is (a) False |
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| 125. |
Which of the following is correct with respect to the genetic material of Φ174 bacteriophage?(a) ss DNA, linear(b) ss RNA, linear(c) ss DNA, circular(d) ds DNA, linearThe question was asked in homework.This is a very interesting question from Molecular Basis of Inheritance topic in section Molecular Basis of Inheritance of Biology – Class 12 |
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Answer» The correct choice is (c) ss DNA, CIRCULAR |
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| 126. |
How many numbers of nucleotides are present in Lambda phage?(a) 48502 bp(b) 98526 bp(c) 10000 bp(d) 5326 bpI have been asked this question at a job interview.This interesting question is from Molecular Basis of Inheritance in section Molecular Basis of Inheritance of Biology – Class 12 |
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Answer» The CORRECT CHOICE is (a) 48502 bp |
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| 127. |
How many base pairs are present in Escherichia coli?(a) 9856 bases(b) 4.6 x 10^6 bp(c) 3.3 x 10^9 bp(d) 10,000 basesI had been asked this question by my college director while I was bunking the class.Question is taken from Molecular Basis of Inheritance in division Molecular Basis of Inheritance of Biology – Class 12 |
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Answer» Right CHOICE is (b) 4.6 X 10^6 bp |
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| 128. |
Which of the following is the characteristic feature of an organism?(a) Number of RNA(b) Number of protein molecules(c) Length of chromosomes(d) Length of DNAThis question was posed to me during an online interview.My question comes from Molecular Basis of Inheritance in section Molecular Basis of Inheritance of Biology – Class 12 |
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Answer» Correct choice is (d) Length of DNA |
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| 129. |
Which of the following is not a correct statement with respect to DNA?(a) It is a long polymer(b) It is found in the nucleus(c) It is a basic substance(d) First identified by Friedrich MeischerThe question was posed to me during an online interview.This question is from Molecular Basis of Inheritance topic in portion Molecular Basis of Inheritance of Biology – Class 12 |
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Answer» Right choice is (C) It is a BASIC substance |
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| 130. |
Which of the following is not a function of RNA?(a) Messenger(b) Catalysis(c) Adapter(d) ModifierThis question was addressed to me during an online exam.I want to ask this question from Molecular Basis of Inheritance in chapter Molecular Basis of Inheritance of Biology – Class 12 |
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Answer» The CORRECT choice is (d) MODIFIER |
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| 131. |
DNA is the genetic material in all the known viruses.(a) False(b) TrueThe question was asked during an online interview.Question is from Molecular Basis of Inheritance topic in division Molecular Basis of Inheritance of Biology – Class 12 |
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Answer» CORRECT option is (a) False Explanation: No, DNA is not the genetic MATERIAL in all the KNOWN viruses. It is the genetic material in all ORGANISMS except for some viruses, where RNA is the MAJOR genetic material like the riboviruses. |
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| 132. |
How many types of nucleic acids are present in the living systems?(a) One(b) Two(c) Three(d) FourThe question was posed to me in a job interview.My doubt stems from Molecular Basis of Inheritance topic in division Molecular Basis of Inheritance of Biology – Class 12 |
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Answer» The correct option is (b) Two |
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| 133. |
What is the full form of DNA?(a) Degenerative acid(b) Deoxyribonucleic acid(c) Deadly nucleic acid(d) Disoriented acidI got this question in a national level competition.This key question is from Molecular Basis of Inheritance topic in division Molecular Basis of Inheritance of Biology – Class 12 |
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Answer» The correct option is (b) Deoxyribonucleic ACID |
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| 134. |
In which year, the mechanism for genetic inheritance reached the molecular level?(a) 1986(b) 1999(c) 1926(d) 1945I have been asked this question during an internship interview.This question is from Molecular Basis of Inheritance topic in portion Molecular Basis of Inheritance of Biology – Class 12 |
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Answer» RIGHT CHOICE is (c) 1926 To explain I WOULD say: The quest to determine the mechanism for GENETIC inheritance reached the molecular level in 1926. The nature of the genetic material was studied at that TIME and it was realised that DNA is the genetic material for the majority of organisms. |
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| 135. |
Who was the first person to analyse factors?(a) Gross(b) Haeckel(c) Mendel(d) AltmannThis question was addressed to me during an interview.This intriguing question comes from Molecular Basis of Inheritance in division Molecular Basis of Inheritance of Biology – Class 12 |
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Answer» RIGHT choice is (c) Mendel To explain: The first person to ANALYSE and DETECT factors was Mendel. In FACT, he was the person who gave the term factors. They were detected by following their patterns of transmission from GENERATION to generation. |
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