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Xenobiotics metabolism phase1 and phase 2 reaction

Answer»

CONJUGATION REACTIONS PREPAREXENOBIOTICS FOR EXCRETION INPHASE 2 OF THEIR METABOLISM. Inphase 1 reactions, XENOBIOTICS are GENERALLY converted to more polar, hydroxylated derivatives. In phase 2 reactions, these derivatives are conjugated with molecules such as glucuronic acid, sulfate, or glutathione.



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