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Write tge chemical equations of willgerodt reaction |
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Answer» The Willgerodt Reactionallows the synthesis of amides from ARYL ketones under the influence ofa secondary amine and a thiating agent. The mechanism involves theformation of an enamine which undergoes thiation, and the CARBONYL groupmigrates to the END of the chain via a CASCADE of thio-substitutediminium-aziridinium rearrangements. |
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