1.

Write a compregensive note on positive super coiling and its important for archaebacteria​

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Positive DNA supercoiling promotes unwrapping of DNA from the histones and modifies NUCLEOSOME STRUCTURE in VITRO; in contrast nucleosomes rapidly form on negatively supercoiled DNA [16]. Consequently, it was SUGGESTED that at each round of transcription, the positive supercoiling is pushed ahead of RNA polymerase



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