Write a brief account of Klinefelter’s syndrome.

1.	Write a brief account of Klinefelter’s syndrome.
Answer» 1. Klinefelter’s syndrome is a genetic disorder caused due to trisomy of X chromosome. 2. It was first described by Harry Klinefelter. 3. Klinefelter’s syndrome is caused due to non-disjunction of sex chromosomes which takes place during gamete formation. 4. Chromosomal complement of Klinefelter’s syndrome is 44+XXY, having a total of 47 chromosomes. Symptoms of Klinefelter’s syndrome are as follows: 1. The Klinefelter’s syndrome individuals are tall, thin and eunuchoid 2. They are sterile with poorly developed sexual characteristics. 3. Testes are underdeveloped and small. Spermatogenesis does not take place. 4. They have subnormal intelligence and show partial mental retardation.

Answer»

1. Klinefelter’s syndrome is a genetic disorder caused due to trisomy of X chromosome.

2. It was first described by Harry Klinefelter.

3. Klinefelter’s syndrome is caused due to non-disjunction of sex chromosomes which takes place during gamete formation.

4. Chromosomal complement of Klinefelter’s syndrome is 44+XXY, having a total of 47 chromosomes.

Symptoms of Klinefelter’s syndrome are as follows:

1. The Klinefelter’s syndrome individuals are tall, thin and eunuchoid

2. They are sterile with poorly developed sexual characteristics.

3. Testes are underdeveloped and small. Spermatogenesis does not take place.

4. They have subnormal intelligence and show partial mental retardation.

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