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Which of the following will be the pharmacokinetic application of prodrugs?(a) Improvement of taste(b) Improvement of odour(c) Site-specific drug delivery(d) Reduction in GI irritationI got this question during an online exam.My enquiry is from Prodrugs topic in section Prodrugs & Excretion of Drugs of Drug Biotechnology

Answer»

Correct option is (c) Site-specific drug delivery

The explanation: Pharmaceutical applications are those where the UNDESIRABLE properties and the physicochemical problems can be SOLVED. These are, for example, improving taste, ODOUR, change of PHYSICAL form, reduction in GI irritation, reduction of pain on INJECTION. Pharmacokinetic applications are such as enhancement of bioavailability, prevention of presystemic metabolism, prolongation of the duration of action, reduction of toxicity, etc.



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