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Which of the following mRNA will not be polyadenylated?(a) Actin mRNA(b) Receptor mRNA(c) Canonical histone mRNA(d) Transport channel mRNAThe question was posed to me by my school principal while I was bunking the class.This interesting question is from Post-Transcriptional Modification in section Gene Expression : Transcription Prokaryotes of Cytogenetics

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Correct option is (c) Canonical HISTONE mRNA

For EXPLANATION: Most of the MRNAS are polyadenylated except the major histone mRNAs. These are the canonical mRNA that NEED a rapid TURNOVER and have a unique 3’ end. However, the non-canonical mRNA produced during S phase are polyadenylated.



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