1.

Which of the following is a required substrate for purine biosynthesis?5-methylthymidine Ribose-5-phosphate 5-phosphoribosyl-1-pyrophosphate 5-fluorouracil 

Answer»

The correct option is (2) Ribose-5-phosphate.

Purine synthesis is a ten-step process that requires ribose-5-phosphate from the PPP, glycine and formate from the serine/glycine synthesis pathway, glutamine, and TCA cycle-derived aspartate.



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