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Which of the following is a non-competitive inhibitor against protease produced by HIV?(a) Tipranavir(b) Acetylcholinesterase(c) Ritonavir(d) Phenicols |
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Answer» The correct answer is (a) Tipranavir To elaborate: In noncompetitive inhibition, the substrate and inhibitor do not compete for the active site of the enzyme and the inhibitor generally act at other site to bind to the enzyme. The level of inhibition depends on concentration of the inhibitor. Tipranavir is non-competitive inhibitor of the protease produced by HIV when HIV infects a white blood cell. Ritonavir is a competitive inhibitor of the protease and resembles the its peptide substate. |
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