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Which drugs bind to RBC membrane?(a) Pentobarbital(b) Acetazolamide(c) Imipramine(d) PhenytoinThis question was addressed to me during an interview for a job.This intriguing question comes from Plasma Protein Drug Binding topic in section Protein Binding of Drugs of Drug Biotechnology

Answer»

The correct OPTION is (c) Imipramine

For explanation: The red blood cell comprises of 3 components each can bind to different KIND of drugs. HAEMOGLOBIN, Carbonic ANHYDRASE, and cell membrane. The cell membrane is reported to bind with CHLORPROMAZINE and imipramine.



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