The maindifference between unicellularandmulticellular issome organisms are made-upofsingle cell termed asunicellularwhile multicellularare made-upoftwo or more cells.Single celledorganismis calledunicellularorganism. They depend on simple diffusion to ride out and live.

difference 1:-1.unicellular organisms are single celled organisms.2.multicellular organisms have more than one cell.

difference 2:-1.the unicellular organisms do various activities on its own.2.multicellular organisms depend on other cells to perform various activities.

difference 3:-1.unicellular organisms include eukaryotes and prokaryotes2.multicellular organisms include eukaryotic cells only.

difference 4:-1.unicellular organisms contain nucleus and some other components.2.but multicellular organisms contain all components like mitochondria so on.

difference 5:-1.unicellular organisms reproduce by asexual reproduction.2.multicellular organisms reproduce by sexual reproduction.

difference 6:-1.ex.amoeba, bacteria , paramaecium .... etc. are examples for unicellular organisms.2.plants,animals,zygote,including humanbeings are examples of multicellular organisms.

difference 7:-1.an injury of unicellular organisms affect the whole body which cause to death.2.an injury of cell in multicellular organisms doesnot affect the whole body.

difference 8:-1.life period is very short in unicellular organisms.2.life period is larger than the unicellular organisms in multicelled.

difference 91.unicellular organisms donot have certain shape2.multicellular organisms have definite shape.

difference 10

1.unicellular includes hetrotrophic.2.multicellular organisms includes both autotrophic and hetrotrophic.