Saved Bookmarks
| 1. |
What is N-Halosuccinamide |
|
Answer» An expedient one-step SYNTHESIS of 2-iodoglycals and 2-bromoglycals from glycals using NIS/AgNO3 and NBS/AgNO3 as reagent systems has been DEVELOPED. The UTILITY of these 2-haloglycals has been demonstrated by converting them into 2C-branched glycals via the Heck coupling REACTION. Ferrier reaction of tri-O-acetyl-2-iodoglycals followed by Heck coupling reaction with methyl acrylate leads to 2C-branched O-glycosides. |
|