What is multiple allelism? Explain with example of ABO blood group sys

What is multiple allelism? Explain with example of ABO blood group system in humans.

Answer»

Multiple Allelism:

i. More than two alternative forms (alleles) of gene in a population occupying the same locus on a chromosome or its homologue are known as multiple alleles.

ii. ABO blood group system in humans is an example of multiple allelism, because gene I exists in three allelic forms IA, IB and IO.

iii. Here, allele I^A codes for type A blood, allele I^B codes for type B blood and allele I^O codes for type O blood.

iv. Allele I^O is recessive to the alleles I^A and I^B .

v. Thus, with these three alleles, we can have 6 different genotypes and 4 different phenotypes for blood groups.

vi.

No.	Genotype	Phenotype (Blood group)
i.	I^A I^A or I^A I^O	Type A
ii.	I^B I^B or I^B I^O	Type B
iii.	I^A I^B	Type AB
iv.	I^O I^O	Type O

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