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What is hnRNA? Explain the changes hnRNA undergoes during its processing to form mRNA. |
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Answer» hnRNA is the precursor of mRNA that is transcribed by RNA ploymerase II and is called heterogenous nuclear RNA. Changes: • The hnRNA undergoes two additional processes called capping and tailing. • In capping, an unusual nucleotide, methyl guanosine triphosphate, is added to the 5'- end of hnRNA. • In tailing, adenylate residues (about 200–300) are added at 3'-end in a template independent manner. • Now the hnRNA undergoes a process where the introns are removed and exons are joined to form mRNA by the process called splicing. Fragments on one of the template strands. |
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