1.

What is hnRNA? Explain the changes hnRNA undergoes during its processing to form mRNA.

Answer»

hnRNA is the precursor of mRNA that is transcribed by RNA ploymerase II and is called heterogenous nuclear RNA. 

Changes: 

• The hnRNA undergoes two additional processes called capping and tailing. 

• In capping, an unusual nucleotide, methyl guanosine triphosphate, is added to the 5'- end of hnRNA. 

• In tailing, adenylate residues (about 200–300) are added at 3'-end in a template independent manner. 

• Now the hnRNA undergoes a process where the introns are removed and exons are joined to form mRNA by the process called splicing. Fragments on one of the template strands.



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