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VEGFR, a receptor tyrosine kinase, is required for the formation of new blood vessels.Activity of VEGFR-mediated signaling is often high in tumors, enabling them to obtain thenutrients necessary for growth. Which of the following would be the best therapeutic strategyfor inhibiting VEGFR-mediated signaling?A) GTPγS, a non-hydrolyzable analogue of GTPB) A drug that inhibits calmodulinC) A drug that inhibits this pathway’s GAPD) A drug that inhibits this pathway’s GEFE) A drug that inhibits the receptor’s phosphatase |
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