The conversion of an amide to an amine with one carbon atom less by the action of alkaline hydrohalite is known as Hofmann bromamide degradation In this reaction, RCONBr is formed from which the reaction has derived its name. Hofmann degradation is an intra molecular reaction. Which is the rate determining step in Hofman bromamide degradiation ?

The conversion of an amide to an amine with one carbon atom less by th

1.	The conversion of an amide to an amine with one carbon atom less by the action of alkaline hydrohalite is known as Hofmann bromamide degradation In this reaction, RCONBr is formed from which the reaction has derived its name. Hofmann degradation is an intra molecular reaction. Which is the rate determining step in Hofman bromamide degradiation ?
Answer» Formation of (i) Formation of (ii) Formation of (iii) Formation of (iv) Solution :CONVERSION of (ii) to (iv) INVOLVING REARRANGEMENT is the SLOWEST step species (iii) is electron dificient DUE to the presence of only 6 electrons on nitrogen. Hence it has a tendency to get its octet completed by migration of alkyl group.