1.

Thalassemic patients produce excess alpha or beta subunits of haemoglobin leading to impaired oxygen-binding capacity by their erythrocytes. How can the subunit produced in excess be determined?

Answer»

Normal and thallasaemic erythrocytes obtained and their lysates analysed 

Protein fingerprinting/2-D gel electrophoresis/MALDI-TOF/SDS-PAGE can identify if α or β chain is absent.



Discussion

No Comment Found

Related InterviewSolutions