1.

Study the mRNA segment given above which is complete to be translated into a polypeptide chain. i. Write the codons ‘a’ and ‘b’. ii. What do they code for ? iii. How is peptide bond formed between two amino acids in the ribosome?

Answer»

i. a is AUG and b is UAA/UAG/UGA 

ii. AUG codes for methionine (initiation codon). UAA/UAG/UGA do not code for any amino acid, i.e., stop or terminating codons. 

iii. There are two sites (P-site and A-site) in the large subunit of ribosome, where subsequent amino acids bind to and thus are close enough to form peptide bond by peptidyl transferase enzyme. The ribosome also acts as a catalyst for the formation of peptide bond.



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