About a month ago I had a new hard drive installed in my computer. I have the following:
XP SP2
McAfees (Issued thru my HUSBANDS employer)
Spybot search and destroy
Windows Firewall Active
DSL computer usually always on

Came home tonight and found a on access scan log from McAfees up. Would let me close it or clean it or deleted. Said it was a generic dropper or generic.dx I couldn't open McAfees, Spybot or anything and it would let me shut down the system. I had to hold in the power button to shut down and then when I turned it back on I recieved numberous error messages. Isass.exe Application Error
wmipruse.exe Application Error
RUNDLL error loading
If I tried to close these then another error cameup that said the system would shut down and restart in so many seconds and it would go through it all again. I was able to get in to McAffees On Demand Scan at the beginning of one of the Startups and it found and tried to delete the Generic downloader but cleaning and deleting both failed.
Here is the HiJack this log
Logfile of Trend Micro HijackThis v2.0.2
Scan saved at 12:20:49 AM, on 3/7/2009
Platform: Windows XP SP2 (WinNT 5.01.2600)
MSIE: Internet Explorer v6.00 SP2 (6.00.2900.2180)
Boot mode: Normal

Running processes:
C:\WINDOWS\System32\smss.exe
C:\WINDOWS\system32\winlogon.exe
C:\WINDOWS\system32\services.exe
C:\WINDOWS\system32\lsass.exe
C:\WINDOWS\system32\Ati2evxx.exe
C:\WINDOWS\system32\svchost.exe
C:\WINDOWS\System32\svchost.exe
C:\WINDOWS\system32\Ati2evxx.exe
C:\WINDOWS\Explorer.EXE
C:\WINDOWS\system32\spoolsv.exe
C:\Program Files\Common Files\Real\Update_OB\realsched.exe
C:\Program Files\MCAFEE\Common Framework\UdaterUI.exe
C:\Program Files\HP\HP Software Update\HPwuSchd2.exe
C:\Program Files\QuickTime\qttask.exe
C:\Program Files\ScanSoft\OmniPageSE2.0\OpwareSE2.exe
C:\Program Files\Canon\MyPrinter\BJMyPrt.exe
C:\Program Files\Java\jre6\bin\jusched.exe
C:\Program Files\Verizon\McciTrayApp.exe
C:\Program Files\McAfee\Common Framework\McTray.exe
C:\Program Files\Messenger\msmsgs.exe
C:\WINDOWS\system32\ctfmon.exe
C:\Program Files\Spybot - Search & Destroy\TeaTimer.exe
C:\Documents and Settings\Compaq_Owner\My Documents\Common\Bin\WinCinemaMgr.exe
C:\Documents and Settings\Compaq_Owner\My Documents\Downloads\Picture Package Menu\SonyTray.exe
C:\Documents and Settings\Compaq_Owner\My Documents\Downloads\Picture Package Applications\Residence.exe
C:\Program Files\Java\jre6\bin\jqs.exe
C:\Program Files\McAfee\Common Framework\FrameworkService.exe
C:\Program Files\McAfee\VirusScan Enterprise\Mcshield.exe
C:\Program Files\McAfee\VirusScan Enterprise\VsTskMgr.exe
C:\Program Files\Common Files\Microsoft Shared\VS7DEBUG\MDM.EXE
C:\WINDOWS\system32\svchost.exe
C:\WINDOWS\system32\wuauclt.exe
C:\WINDOWS\ALCXMNTR.EXE
C:\Program Files\ATI Technologies\ATI Control Panel\atiptaxx.exe
c:\windows\system\hpsysdrv.exe
C:\Program Files\iTunes\iTunesHelper.exe
C:\Program Files\iPod\bin\iPodService.exe
C:\Program Files\Internet Explorer\iexplore.exe
C:\Program Files\Trend Micro\HijackThis\HijackThis.exe

R1 - HKCU\Software\Microsoft\Internet Explorer\Main,Default_Page_URL = http://ie.redirect.hp.com/svs/rdr?TYPE=3&tp=iehome&locale=EN_US&c=Q405&bd=presario&pf=desktop&parm1=seconduser
R1 - HKCU\Software\Microsoft\Internet Explorer\Main,Default_Search_URL = http://ie.redirect.hp.com/svs/rdr?TYPE=3&tp=iesearch&locale=EN_US&c=Q405&bd=presario&pf=desktop&parm1=seconduser
R1 - HKCU\Software\Microsoft\Internet Explorer\Main,Search Bar = http://ie.redirect.hp.com/svs/rdr?TYPE=3&tp=iesearch&locale=EN_US&c=Q405&bd=presario&pf=desktop&parm1=seconduser
R1 - HKCU\Software\Microsoft\Internet Explorer\Main,Search Page = http://ie.redirect.hp.com/svs/rdr?TYPE=3&tp=iesearch&locale=EN_US&c=Q405&bd=presario&pf=desktop&parm1=seconduser
R0 - HKCU\Software\Microsoft\Internet Explorer\Main,Start Page = http://www.yahoo.com/
R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Default_Page_URL = http://ie.redirect.hp.com/svs/rdr?TYPE=3&tp=iehome&locale=EN_US&c=Q405&bd=presario&pf=desktop&parm1=seconduser
R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Default_Search_URL = http://ie.redirect.hp.com/svs/rdr?TYPE=3&tp=iesearch&locale=EN_US&c=Q405&bd=presario&pf=desktop&parm1=seconduser
R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Search Bar = http://ie.redirect.hp.com/svs/rdr?TYPE=3&tp=iesearch&locale=EN_US&c=Q405&bd=presario&pf=desktop&parm1=seconduser
R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Search Page = http://ie.redirect.hp.com/svs/rdr?TYPE=3&tp=iesearch&locale=EN_US&c=Q405&bd=presario&pf=desktop&parm1=seconduser
R0 - HKLM\Software\Microsoft\Internet Explorer\Main,Start Page = http://ie.redirect.hp.com/svs/rdr?TYPE=3&tp=iehome&locale=EN_US&c=Q405&bd=presario&pf=desktop&parm1=seconduser
R0 - HKLM\Software\Microsoft\Internet Explorer\Search,SearchAssistant = http://ie.redirect.hp.com/svs/rdr?TYPE=3&tp=iesearch&locale=EN_US&c=Q405&bd=presario&pf=desktop&parm1=seconduser
R1 - HKCU\Software\Microsoft\Windows\CurrentVersion\Internet Settings,ProxyOverride = localhost
O1 - HOSTS: 195.245.119.131 browser-security.microsoft.com
O2 - BHO: AcroIEHlprObj Class - {06849E9F-C8D7-4D59-B87D-784B7D6BE0B3} - C:\Program Files\Adobe\Acrobat 7.0\ActiveX\AcroIEHelper.dll
O2 - BHO: Spybot-S&D IE Protection - {53707962-6F74-2D53-2644-206D7942484F} - C:\PROGRA~1\SPYBOT~1\SDHelper.dll
O2 - BHO: Java(tm) Plug-In SSV HELPER - {761497BB-D6F0-462C-B6EB-D4DAF1D92D43} - C:\Program Files\Java\jre6\bin\ssv.dll
O2 - BHO: scriptproxy - {7DB2D5A0-7241-4E79-B68D-6309F01C5231} - C:\Program Files\McAfee\VirusScan Enterprise\Scriptcl.dll
O2 - BHO: Google Toolbar Helper - {AA58ED58-01DD-4d91-8333-CF10577473F7} - c:\program files\google\googletoolbar1.dll
O2 - BHO: Java(tm) Plug-In 2 SSV Helper - {DBC80044-A445-435b-BC74-9C25C1C588A9} - C:\Program Files\Java\jre6\bin\jp2ssv.dll
O2 - BHO: JQSIEStartDetectorImpl - {E7E6F031-17CE-4C07-BC86-EABFE594F69C} - C:\Program Files\Java\jre6\lib\deploy\jqs\ie\jqs_plugin.dll
O3 - Toolbar: &Google - {2318C2B1-4965-11d4-9B18-009027A5CD4F} - c:\program files\google\googletoolbar1.dll
O4 - HKLM\..\Run: [HPBootOp] "C:\Program Files\Hewlett-Packard\HP Boot Optimizer\HPBootOp.exe" /run
O4 - HKLM\..\Run: [LSBWatcher] c:\hp\drivers\hplsbwatcher\lsburnwatcher.exe
O4 - HKLM\..\Run: [TkBellExe] "C:\Program Files\Common Files\Real\Update_OB\realsched.exe"  -osboot
O4 - HKLM\..\Run: [ShStatEXE] "C:\Program Files\McAfee\VirusScan Enterprise\SHSTAT.EXE" /STANDALONE
O4 - HKLM\..\Run: [McAfeeUpdaterUI] "C:\Program Files\McAfee\Common Framework\UdaterUI.exe" /StartedFromRunKey
O4 - HKLM\..\Run: [HP Software Update] C:\Program Files\HP\HP Software Update\HPwuSchd2.exe
O4 - HKLM\..\Run: [QuickTime Task] "C:\Program Files\QuickTime\qttask.exe" -atboottime
O4 - HKLM\..\Run: [OpwareSE2] "C:\Program Files\ScanSoft\OmniPageSE2.0\OpwareSE2.exe"
O4 - HKLM\..\Run: [CanonSolutionMenu] C:\Program Files\Canon\SolutionMenu\CNSLMAIN.exe /logon
O4 - HKLM\..\Run: [CanonMyPrinter] C:\Program Files\Canon\MyPrinter\BJMyPrt.exe /logon
O4 - HKLM\..\Run: [SunJavaUpdateSched] "C:\Program Files\Java\jre6\bin\jusched.exe"
O4 - HKLM\..\Run: [Verizon_McciTrayApp] C:\Program Files\Verizon\McciTrayApp.exe
O4 - HKLM\..\Run: [UserFaultCheck] %systemroot%\system32\dumprep 0 -u
O4 - HKLM\..\RunOnce: [SpybotSnD] "C:\Program Files\Spybot - Search & Destroy\SpybotSD.exe" /autocheck
O4 - HKCU\..\Run: [MSMSGS] "C:\Program Files\Messenger\msmsgs.exe" /background
O4 - HKCU\..\Run: [ctfmon.exe] C:\WINDOWS\system32\ctfmon.exe
O4 - HKCU\..\Run: [rundll32.exe] rundll32.exe "C:\Documents and Settings\Compaq_Owner\Application Data\Macromedia\Common\97f9a0721.dll""
O4 - HKCU\..\Run: [system tool] C:\WINDOWS\sysguard.exe
O4 - HKCU\..\Run: [SpybotSD TeaTimer] C:\Program Files\Spybot - Search & Destroy\TeaTimer.exe
O4 - HKCU\..\Policies\Explorer\Run: [svcho] C:\WINDOWS\svcho.exe
O4 - HKUS\S-1-5-19\..\Run: [rundll32.exe] rundll32.exe "C:\Documents and Settings\LocalService\Application Data\Macromedia\Common\97f9a0721.dll"" (User 'LOCAL SERVICE')
O4 - HKUS\S-1-5-20\..\Run: [rundll32.exe] rundll32.exe "C:\Documents and Settings\NetworkService\Application Data\Macromedia\Common\97f9a0721.dll"" (User 'NETWORK SERVICE')
O4 - HKUS\S-1-5-18\..\Run: [rundll32.exe] rundll32.exe "C:\WINDOWS\system32\config\systemprofile\Application Data\Macromedia\Common\97f9a0721.dll"" (User 'SYSTEM')
O4 - HKUS\.DEFAULT\..\Run: [rundll32.exe] rundll32.exe "C:\WINDOWS\system32\config\systemprofile\Application Data\Macromedia\Common\97f9a0721.dll"" (User 'Default user')
O4 - Startup: ChkDisk.lnk = ?
O4 - Global Startup:  WinCinema Manager.lnk = C:\Documents and Settings\Compaq_Owner\My Documents\Common\Bin\WinCinemaMgr.exe
O4 - Global Startup: Microsoft Office.lnk = C:\Program Files\Microsoft Office\Office\OSA9.EXE
O4 - Global Startup: Picture Package Menu.lnk = ?
O4 - Global Startup: Picture Package VCD Maker.lnk = ?
O8 - Extra context menu item: &Google Search - res://C:\Program Files\Google\GoogleToolbar1.dll/cmsearch.html
O8 - Extra context menu item: Add to Google Photos Screensa&ver - res://C:\WINDOWS\system32\GPhotos.scr/200
O8 - Extra context menu item: Backward Links - res://C:\Program Files\Google\GoogleToolbar1.dll/cmbacklinks.html
O8 - Extra context menu item: Cached Snapshot of Page - res://C:\Program Files\Google\GoogleToolbar1.dll/cmcache.html
O8 - Extra context menu item: E&xport to Microsoft Excel - res://C:\PROGRA~1\MI1933~1\OFFICE11\EXCEL.EXE/3000
O8 - Extra context menu item: Similar Pages - res://C:\Program Files\Google\GoogleToolbar1.dll/cmsimilar.html
O8 - Extra context menu item: Translate into English - res://C:\Program Files\Google\GoogleToolbar1.dll/cmtrans.html
O9 - Extra button: (no name) - {DFB852A3-47F8-48C4-A200-58CAB36FD2A2} - C:\PROGRA~1\SPYBOT~1\SDHelper.dll
O9 - Extra 'Tools' menuitem: Spybot - Search & Destroy Configuration - {DFB852A3-47F8-48C4-A200-58CAB36FD2A2} - C:\PROGRA~1\SPYBOT~1\SDHelper.dll
O9 - Extra button: Connection Help - {E2D4D26B-0180-43a4-B05F-462D6D54C789} - C:\WINDOWS\PCHEALTH\HELPCTR\Vendors\CN=Hewlett-Packard,L=Cupertino,S=Ca,C=US\IEButton\support.htm
O9 - Extra 'Tools' menuitem: Connection Help - {E2D4D26B-0180-43a4-B05F-462D6D54C789} - C:\WINDOWS\PCHEALTH\HELPCTR\Vendors\CN=Hewlett-Packard,L=Cupertino,S=Ca,C=US\IEButton\support.htm
O9 - Extra button: Messenger - {FB5F1910-F110-11d2-BB9E-00C04F795683} - C:\Program Files\Messenger\msmsgs.exe
O9 - Extra 'Tools' menuitem: Windows Messenger - {FB5F1910-F110-11d2-BB9E-00C04F795683} - C:\Program Files\Messenger\msmsgs.exe
O23 - Service: Ati HotKey Poller - ATI Technologies Inc. - C:\WINDOWS\system32\Ati2evxx.exe
O23 - Service: Google Updater Service (gusvc) - Google - C:\Program Files\Google\Common\Google Updater\GoogleUpdaterService.exe
O23 - Service: InstallDriver Table Manager (IDriverT) - Macrovision Corporation - C:\Program Files\Common Files\InstallShield\Driver\1050\Intel 32\IDriverT.exe
O23 - Service: iPod Service (iPodService) - Apple Computer, Inc. - C:\Program Files\iPod\bin\iPodService.exe
O23 - Service: Java Quick Starter (JavaQuickStarterService) - Sun Microsystems, Inc. - C:\Program Files\Java\jre6\bin\jqs.exe
O23 - Service: McAfee Framework Service (McAfeeFramework) - McAfee, Inc. - C:\Program Files\McAfee\Common Framework\FrameworkService.exe
O23 - Service: McAfee McShield (McShield) - McAfee, Inc. - C:\Program Files\McAfee\VirusScan Enterprise\Mcshield.exe
O23 - Service: McAfee Task Manager (McTaskManager) - McAfee, Inc. - C:\Program Files\McAfee\VirusScan Enterprise\VsTskMgr.exe

--
End of file - 10625 bytes
  

This all seemed to start around 6PM ESt. and no one was home to have even been on the computer at this time. Any help would be appreciated and if there are anyother security items that I should have preferrably free downloads please let me know.

Thanks
Fran