I cannot run MANY programs, including team-viewer or Trojan killer or word or excel, etc....When I try, I get the following 2 messages...:::::::::

Under heading "Microsoft Works"  message reads (Cannot change the DOCUMENT C:/Program...\trojankiller.exe.  The document is read-only or is open by  another user or application.  To change this file, save it with a different filename.)

I then hit OK and another box pops up under the heading of Microsoft works spreadsheet....
(Works cannot open the file you selected.  The file may be corrupted or it may be a file type that the spreadsheet cannot open.  Check that the file type appears in the DROP down LIST in the file open dialog.)

Sometimes I can get a program to work by right clicking the icon and opening another way. many times I just can't get the program to work....no big deal as I have a new laptop and will be giving my old one away.....but it would be nice if I gave it away working......

I can also get IE or Firefox to work....
Running on 9 year old emachine desktop pc... "xp" 
I have tried rebooting, samething....also, tried to restore but can't get the restore program to run, same message as above...Last resort, I may take original disk from when I bought it and see what it may do?

Any Ideas???   
HipDo you have an XP CD?

If so, place it in your CD ROM drive and follow the instructions below:
•Click on Start > Run and type sfc /scannow then press Enter (note the space between scf and /scannow)
*Let this run undisturbed until the window with the blue  progress bar goes away
SFC - Which stands for System File Checker, retrieves the correct version of the file from %Systemroot%\System32\Dllcache or the Windows installation source files, and then replaces the incorrect file.Thanks for the response...  I loaded the original restore cd and types what you described.....  It does the same thing as I described above.....  It won't run the scan....

also tried GHO fix programs and same thing, download them but they won't run.....
??     HipCan you boot the computer in Safe Mode?Sounds like the ".exe" file extension has been WRONGLY associated to Microsoft Works.

Try uninstalling Work (or office) and then re-installing.

I'd say it's worth a shot.