Optical isomerisms examples

1.	Optical isomerisms examples
Answer» Answer: OPTICAL isomers are used EXTENSIVELY in medicine. ... EXAMPLES are: the volume of distribution of (R)-methadone is 2x more than that that of (S)-methadone due to lower plasma BINDING and increased tissue binding. the clearance of (R)-fluoxetine is about 4x greater than (S)-fluoxetine due to a higher rate of enzyme metabolism.

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Answer:

OPTICAL isomers are used EXTENSIVELY in medicine.

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the volume of distribution of (R)-methadone is 2x more than that that of (S)-methadone due to lower plasma BINDING and increased tissue binding.

the clearance of (R)-fluoxetine is about 4x greater than (S)-fluoxetine due to a higher rate of enzyme metabolism.

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