In the given picture of a graph plotted between the plasma concentrations versus time, the marked curve is for which kind of dosage?(a) Larger dose(b) Optimum dose(c) Smaller dose(d) Lethal doseI got this question in an internship interview.The doubt is from Pharmacokinetic Principles Applications in division Applications of Pharmacokinetic Principles, Diuretics, Drug Concentration and Pharmacologic Response of Drug Biotechnology

In the given picture of a graph plotted between the plasma concentrati

1.	In the given picture of a graph plotted between the plasma concentrations versus time, the marked curve is for which kind of dosage?(a) Larger dose(b) Optimum dose(c) Smaller dose(d) Lethal doseI got this question in an internship interview.The doubt is from Pharmacokinetic Principles Applications in division Applications of Pharmacokinetic Principles, Diuretics, Drug Concentration and Pharmacologic Response of Drug Biotechnology
Answer» CORRECT option is (B) Optimum dose The explanation is: The marked curve is showing the profile for optimum dose profile. The optimum dose is therapeutically successful. It does not show LARGER fluctuations neither it reaches the toxic concentration. The curve in the UPPER side is for larger dose profile. The curve below that is for smaller dose profile.

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