How are the following enzymes activated in the alimentary canal? (i)

1.	How are the following enzymes activated in the alimentary canal? (i) pepsinogen (ii) Carboxypeptidase, (iii) prorennin, (iv) trypsinogen and chymotrypsinogen.
Answer» (i) Pepsinogen: Pepsinogen becomes activated as soon as the food reaches the stomach i.e., as soon as the secretion of HCI takes place. It acts most effectively within the pH range of 1.6-3.2. (ii) PrCarboxypeptidase: Trypsin activates carboxy-peptidase. (iii) Rennin: It is secreted as prorennin but HCl present in the gastric juice converts inactive prorennin into active rennin. (iv) Trypsinogen and Chymotrypsinogen: These are inactive enzymes until they come in contact with enteropeptidase(intestinal enzyme) which converts them into active trypsin and chymotrypsin.

How are the following enzymes activated in the alimentary canal? (i) pepsinogen (ii) Carboxypeptidase, (iii) prorennin, (iv) trypsinogen and chymotrypsinogen.

Answer»

(i) Pepsinogen: Pepsinogen becomes activated as soon as the food reaches the stomach i.e., as soon as the secretion of HCI takes place. It acts most effectively within the pH range of 1.6-3.2.

(ii) PrCarboxypeptidase: Trypsin activates carboxy-peptidase.

(iii) Rennin: It is secreted as prorennin but HCl present in the gastric juice converts inactive prorennin into active rennin.

(iv) Trypsinogen and Chymotrypsinogen: These are inactive enzymes until they come in contact with enteropeptidase(intestinal enzyme) which converts them into active trypsin and chymotrypsin.

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