1.

For palindromic sequences, what is the structure of the dot plot?(a) 2 intersecting diagonal lines at the midpoint(b) One diagonal(c) Two parallel diagonals(d) No diagonalI have been asked this question in an online interview.This question is from Dot Matrix Sequence Comparison in portion Sequence Alignment of Bioinformatics

Answer»

Right option is (a) 2 intersecting diagonal lines at the MIDPOINT

To elaborate: For perfectly aligned sequences there is a diagonal formation of dot plot. For PALINDROMIC sequences i. E. for sequences that are SYMMETRICAL from the midpoint of the sequence, there exist 2 intersecting diagonals on the plot.



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