1.

Explain the processing the hnRNA needs to undergo before becoming functional mRNA in eukaryotes.

Answer»

The precursor of mRNA i.e. hnRNA contains both introns and exons. Introns are removed and exons are joined by a process called splicing. The remaining mRNA is processed in two ways : 

(i) Capping : Here, an unusual nucleotide called methyl guanosine triphosphate (cap) is added to the 5' end of hnRNA. 

(ii) Tailing : Here, adenylate residues (200-300) are added at 3' end of hnRNA in a template independent manner. 

When hnRNA is fully processed, it is known as mRNA, which is transported out of the nucleus to get translated.



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