1.

Explain the procedure by which PCR aids in early detection of cancer.

Answer»
  • A single stranded DNA or RNA is tagged with a radioactive molecule(probe)
  • It is allowed to hybridize to its complementary DNA in a clone of cells followed by detection using autoradiography.
  • The clone having the mutated gene will hence not appear on the photographic film,
  • because the probe will not have complementarity with the mutated gene.

Hence, cancer induced mutation can be detected.



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