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Ester given nucleophilic additionreactionfollowed by eliminationreaction withcarbon nucleophile . Whencarbon nucleophileis of anesterthenthe reactionis knowas Claisencondensationreaction. This reactions is alsocarrieout betweenester and aketone. Asuccessful Claisencondensationrequires an ester withtwo alpha- hydrogensand aan equivalentamountof base ratherthan acatayticamount of base . IntramolecularClaisencondensationgivenby diesteris known as: |
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Answer» Stoblecondensation |
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