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Enzyme abnormalities of the glycolytic pathways and anaemia

Answer»

Disorders of the glycolytic pathway. Mutations of most of the enzymes in the glycolytic pathway have been DESCRIBED in association with congenital non-spherocytic haemolytic anaemia (CNSHA). HOWEVER, DEFICIENCY of pyruvate KINASE (PK) is far and away the most COMMON defect.



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