| Epithalamus | hypothalamus |
| 1. Epithalamus is the roof of diencephalon. | 1. Hypothalamus is the floor of diencephalon. |
| 2. Epithalamus shows pineal stalk to which pineal gland is attached. | 2. Hypothalamus shows infundibulum to which pituitary gland is attached. |
| 3. Epithalamus is nonnervous in nature. | 3. Hypothalamus is the higher centre of autonomous nervous system. |
| 4. Epithalamus has anterior choroid plexus which secretes cerebrospinal fluid. | 4. Hypothalamus has neurons which secrete two endocrine hormones. |
| 5. Epithalamus controls biological rhythm. | 5. Hypothalamus controls homeostasis of the body. |
