| Prokaryotic | Eukaryotic |
| (i) These cells lack membrane-bound nucleus and other membrane-bound organelles | (i) These cells have membrane-bound nucleus and other membrane-bound organelles |
| (ii) They have 70 S ribosomes | (ii) They have 80 S ribosomes |
| (iii) They have plasmids in addition to genomic DNA | (iii) They have chromosomes which contain DNA |
| (v) Gas vacuoles are present | (v) Sap/food/contractile vacuoles are present |
| (vi) Cell wall is always present and made of peptidoglycan. | (vi) Cell wall is present in plants and absent in animals. |