Differentiate between haemophilia and sickle cell anaemia. – InterviewSolution

1.

Differentiate between haemophilia and sickle cell anaemia.

Answer»

Haemophilia	Sickle cell anaemia
1. It is due to recessive defective allele present on X – chromosome.	1. It is due to point mutation i.e., a single base pair change leading to a change in an aminoaied.
2. It is a sex linked ‘disorder.	2. It is a autosomal disoder.
3. A protein necessary for clotting of blood is deficient.	3. The defective haemoglobin leads to a change in the shape of RBCs, which become sickle celled.

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