1.

Desirable properties of a radionuclide for imaging include: a. High levels of cross-reactivity with blood proteins b. A half-life measured in hours, not minutes or days c. It decays to a stable daughter d. Low activity per unit volume e. Emission of beta particles

Answer»

a. False. This would result in high blood pool activity, which may reduce uptake in the target organ. 

b. True. The half-life should ideally be a few hours, roughly equal to the time from injection to scanning.

c. True. Decay should be to a stable daughter in order to minimize the dose to the patient. 

d. False. A radionuclide should have a high specific activity, i.e. high activity per unit volume. 

e. False. Beta particles act as secondary electrons and deposit an unnecessary dose in patients.



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