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Describe the endocrine role of islets of Langerhans. OR Islets of Langerhans. |
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Answer» Endocrine cells of pancreas form groups of cells called Islets of Langerhans. There are four kinds of cells in islets of Langerhans which secrete hormones. 1. Alpha (α) cells : They are 20% and secrete glucagon. Glucagon is a hyperglycemic hormone. It stimulates liver for glucogenolysis and increases the blood glucose level. 2. Beta (β) cells : They are 70% and secrete insulin. Insulin is a hypoglycemic hormone. It stimulates liver and muscles for glycogenesis. This lowers blood glucose level. 3. Delta (δ) cells : They are 5% and secrete somatostatin. Somatostatin inhibits the secretion of glucagon and insulin. It also decreases the gastric secretions, motility and absorption in digestive tract. In general it is a growth inhibiting factor. 4. PP cells or F cells : They form 5%. They secrete pancreatic polypeptide (PP) which inhibits the release of pancreatic juice. |
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