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Consider a short segment of a wild-type gene with the following nucleotide-pair sequence: 5-ATG TCC GCA TGG GGA -3 3-TAC AGG CGT ACC CCT -5 Transcription of this gene segment yields the following mRNA nucleotide sequence: 5-AUG UCC GCA UGG GGA-3 and translation of this mRNA produces the amino acid sequence: methionine-serine-alanine-tryptophan-glycine.If a single nucleotide-pair substitution occurs in the gene segment , changing the G:C at position 12 to A:T, what effect will this mutation have on the polypeptide produced by this gene?No changeAbnormal proteinSingle amino acid substitutionTruncated protein |
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