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Commonly used vectors for human genome sequencing areA. T/A Cloning VectorsB. T-DNAC. BAC and YACD. Expression Vectors |
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Answer» Correct Answer - C `**" "`For sequencing, the total DNA from a cell is isolated and converted into random fragments of relatively smaller sizes (recall DNA is a very long polymer, and there are technical limitations in sequencing very long pieces of DNA) and cloned in suitable host using specialised vectors. `**" "`The cloning resulted into amplification of each piece of DNA fragment so that it subsequently could be sequenced with ease. `**" "`The commonly used hosts were bacteria and yeast, and the vectors were called as BAC (bacterial artificial chromosomes), and YAC (yeast artificial chromosomes). |
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