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Can the acid chloride of an alpha-amino acid be made by treating it with SOCI_(2) ? |
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Answer» Solution :No. Two molecules of the INITIALLY formed `ALPHA`-amino acid chloride react with each otherf to form a dipeptide acid chloride which , in turn, reacts further to form tetrapeptide acid chloride , ETC. ,brgt `NH_(2)-CHR-COOH+SOCI_(2)to NH_(2)-CHR-COCI +SO_(2)+HCI` `underset("two molecules")underset(alpha-"Amino acid Chloride")(NH_(2) CHRCOCI+NH_(2)CHRCOCI) OVERSET(-HCI)to underset("Dipeptide acid chloride")(NH_(2)CHRCONHCHRCOCIto to to etc)`. |
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