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| 1. |
Can Gatterman-Koch reaction be considered similar to Friedel-Craft acylation? Discuss. |
| Answer» Solution :Yes. Gattermann-Koch reaction can be considered similar to friedel-crafts ACYLATION. The reason being that in F.C. acylation reactions, benzene (or any other arene) is treated with an acid chlorie in presence of ANHYD. `AlCl_(3)`. SINCE HCOCl (FORMYL chloride) is not stable, therefore, in gattermann-koch reaction, it is prepared in situ by reacting CO with HCl gas in presence of anhydrous `AlCl_(3)`. thus, gattermann-Koch reaction is similar to F.C. acylation reaction. | |