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Beta thalassemia occurs due to translocation of beta globin gene? |
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Answer» tion:Mutations that completely inactivate the β gene resulting in no β-globin PRODUCTION cause β0-thalassemia. ... A QUANTITATIVE reduction in β globin RESULTS in the accumulation of excess α-globin chains that are responsible for the PATHOPHYSIOLOGY of the disorder (Thein 2005) |
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