Aryl halides undergo nucleophilic substitution reaction only is extreme condition. Except to certain industrial processes where very severe conditions are feasible, one does not ordinarily prepare phenols (ArOH), ethers (ArOR), amines (ArNH_(2)) or nitriles (ArCN) by nucleophilic attact on aryl halides. The presence of electron withdrawing groups like -NO_(2), -CF_(3) at ortho or para positioin to the halogen atom makes the aryl halides more susceptible to nucleophilic attack. The reaction of unactivated ordeactivated aryl halide with strong bases or at highh temperature proceed via the benzyne intermediate. underset(NH_(3))overset(NaNH_(2))to Product. The predominant product is

Aryl halides undergo nucleophilic substitution reaction only is extrem

1.	Aryl halides undergo nucleophilic substitution reaction only is extreme condition. Except to certain industrial processes where very severe conditions are feasible, one does not ordinarily prepare phenols (ArOH), ethers (ArOR), amines (ArNH_(2)) or nitriles (ArCN) by nucleophilic attact on aryl halides. The presence of electron withdrawing groups like -NO_(2), -CF_(3) at ortho or para positioin to the halogen atom makes the aryl halides more susceptible to nucleophilic attack. The reaction of unactivated ordeactivated aryl halide with strong bases or at highh temperature proceed via the benzyne intermediate. underset(NH_(3))overset(NaNH_(2))to Product. The predominant product is
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