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An amino acid is characterized by two `pKa` values the one corresponding to the more acidic site is designated as `pKa_(1)` and the other corresponding to the less site is designated as `pKa_(2)`. Some amino acids have side chain with acidic or basic groups. These amino acids have `pKa_(3)` value also for the side chain. `|{:(S.No,"Amino acid",P^(Ka1),P^(Ka2),P^(Ka3)" (Side chain)"),(I,"Aspartic acid",1.88,9.6,3.65),(II,"Glutamic acid",2.19,9.67,4.25),(III,"Lysine",2.18,8.95,10.53),(IV,"Arginine",2.17,9.04,12.48):}|` The isoelectric point `(pI)` of Aspartic acid and lysine will be respectively `:`A. 6.35B. 9.74C. 2.77D. 10.76 |
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Answer» Correct Answer - B for basic amino acids `P^1=(P^(Ka_2)+P^(ka_3))/2=(8.95+10.53)/2=19.48/2=9.74` |
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