1.

a. How can microbial cultures be used for the production of different metabolites? b. A recently discovered microbial strain gives us the desired metabolite in nanomolar concentration. Suggest two ways of improving the production of the desired metabolite.

Answer»

a. Production of food, vaccines/ Production of primary metabolites; acids, alcohol/ Production of secondary metabolites: antibiotics/ Biotransformation reactions: enzymatic, steroids 

b. Strain improvement is done in order to maximize metabolite production by: 

  •  Mutant selection : There are two methods - Physical method; Chemical Method 
  • Genetic engineering


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